Research Paper Volume 15, Issue 13 pp 6163—6178

PRMT5 facilitates angiogenesis and EMT via HIF-1α/VEGFR/Akt signaling axis in lung cancer

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Figure 6. Graphic summary of the mechanism by which PRMT5 regulates HIF-1α expression and VEGFR2/Akt/eNOS to promote angiogenesis and metastasis in human lung cancer.