Research Paper Volume 15, Issue 12 pp 5887—5916
Swertia cincta Burkill alleviates LPS/D-GalN-induced acute liver failure by modulating apoptosis and oxidative stress signaling pathways
Figure 12. ESC mechanism against ALF. The mRNA expression of AKT1 (A), EGFR (B), ESR1 (C), HIF1A (D), VGEFA (E), ERBB2 (F), and mTOR (G). And the protein expression levels of p-AKT/AKT (H), p-PI3K/PI3K ratio (I), p-mTOR/mTOR ratio (J), p-EGFR/EGFR ratio (K), p-ERK1/2/ERK1/2 ratio (L), Cyto-Nrf2 (M), Nucle-Nrf2 (N), HO-1 (O), and (P–R) Western blot results. Results of 6 independent experiments were described above, of which the significant ones were recorded as *p < 0.05, **p < 0.01 and #p < 0.05, ##p < 0.01, respectively, for the model group and the control group.