Research Paper Volume 15, Issue 14 pp 6798—6821

Molecular subtypes based on DNA sensors predict prognosis and tumor immunophenotype in hepatocellular carcinoma

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Figure 6. Comparison of ‘hot’ tumor characteristics between C1 and C2 subtypes. (A) IFNG. (B) Merck 18. (C) CD8. (D) PD-L1. (E) Dysfunction. (F) CAF. (G) Exclusion. (H) MDSC. (I) TAM.M2. The asterisks represent the P-value (****p < 0.0001). The statistical analyses were performed by the student t-test. IFNG, interferon-γ; CD8, cluster of differentiation 8; PD-L1, programmed cell death 1 ligand 1; CAF, cancer associated fibroblast; MDSC, myeloid-derived suppressor cells; TAM, tumor associated macrophage.