Research Paper Volume 15, Issue 16 pp 8044—8060

The alleviating effect and mechanism of GLP-1 on ulcerative colitis

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Figure 10. Effects of GLP-1 on DSS-induced colitic mice. The effect of GLP-1 (Green arrows) could alleviate DSS-induced (Red arrows) ulcerative colitis through reducing the secretion of inflammatory cytokines, increase the expression of tight junction proteins and regulating intestinal microbiota.