Research Paper Volume 15, Issue 16 pp 8044—8060

The alleviating effect and mechanism of GLP-1 on ulcerative colitis

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Figure 9. GLP-1 inhibits the phosphorylation of AKT, NF-κB p65, ERK1/2, JNK and P38 in RAW264.7 cells. The protein expression of p-AKT (A, B), p-NF-κB p65 (A, C), p-ERK1/2 (A, D), p-JNK (A, E) and p-P38 (A, F) was estimated by western blotting. The values shown here are the mean value ± SD of three independent experiments. For LPS+GLP-1 induced RAW264.7 cells vs. the LPS group, *p < 0.05 - **p < 0.01 and for LPS-induced RAW264.7 cells vs. the NT group, #p < 0.05 was considered significant.