Research Paper Volume 15, Issue 16 pp 8501—8517
Xuebijing injection protects sepsis induced myocardial injury by mediating TLR4/NF-κB/IKKα and JAK2/STAT3 signaling pathways
Figure 3. The interaction between the five monomer components of XBJ and JAK2/STAT3 signaling pathway. (A–E) The molecular structure of the monomers corresponding to the five components of XBJ: paeoniflorin (A), Succinic acid (B), Quercetin (C), Naringenin (D) and Ferulic acid (E). (F–O) 3D crystal structure for paeoniflorin-JAK2 complex (F), Succinic acid-JAK2 complex (G), Quercetin-JAK2 complex (H), Naringenin-JAK2 complex (I), Ferulic acid-JAK2 complex (J), paeoniflorin-STAT3 complex (K), Succinic acid-STAT3 complex (L), Quercetin-STAT3 complex (M), Naringenin-STAT3 complex (N), and Ferulic acid-STAT3 complex (O).