Research Paper Volume 15, Issue 19 pp 10524—10539

Figure 2. PRXT treatment ameliorated lung pathological injury and improved survival rate in bleomycin-induced mice. (A–D) Analyses of pulmonary function parameters in the indicated groups including specific airway resistance (sRaw), specific airway conductance (sGaw), functional residual capacity (FRC), as well as minute volume (MV) (n=5). (E–G) Analyses of arterial blood gas including PaO₂, PaCO₂, and HCO₃^- in the indicated groups (n=5). *P < 0.05 vs. the Control group, ^#P < 0.05 vs. the PF group. PF, pulmonary fibrosis. PRTX-L, Paroxetine-Low dose (2.5 mg·kg⁻¹·day⁻¹). PRTX-M, Paroxetine-Medium dose (5 mg·kg⁻¹·day⁻¹). PRTX-H, Paroxetine-High dose (7.5 mg·kg⁻¹·day⁻¹).