Research Paper Volume 15, Issue 21 pp 12085—12103

Identification and diagnostic potential of serum microRNAs as biomarkers for early detection of Alzheimer’s disease

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Figure 1. Overall working flowchart of bioinformatics analysis based on publicly available data in GEO public database. GEO, Gene Expression Omnibus; miRNA, microRNA; FC, fold change; RNA22, TargetScant, miRTarBase, microRNA-target interactions database; mRNA, messenger RNA. NC, normal control; MCI, Mild cognitive impairment; AD, Alzheimer’s disease.