Research Paper Volume 15, Issue 21 pp 12264—12274
Influences and mechanism of erythropoietin on the cognitive function of vascular dementia rats
Figure 7. EPO can regulate the oxidative stress in hippocampal neurons, thereby resisting apoptosis and inhibiting inflammatory response through the BDNF/TrKB/PI3K/ERK1/2 axis to effectively ameliorate the cognitive dysfunction caused by chronic hypoperfusion in VD rats.