Research Paper Volume 15, Issue 21 pp 12451—12475

Abnormal low expression of SFTPC promotes the proliferation of lung adenocarcinoma by enhancing PI3K/AKT/mTOR signaling transduction

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Figure 9. Development and verification of nomogram in LUAD. (A, B) Univariate (A) and multivariate (B) regression analysis related to OS of patients in TCGA_LUAD cohort. (CE) In the TCGA LUAD cohort, time-dependent ROC analyses of the patients’ 1- (C), 3- (D), and 5-year (E) survival status based on their risk score and/or clinical characteristics. (F) The C-index curves of risk score and clinical features. (G) The nomogram is based on gender, age, tumor purity, T stage, N stage, M stage, TMB, and risk. (H) Time-dependent ROC analyses of the patients’ 1-, 3-, and 5-year survival status based on the nomogram. (I) The calibration curves of the nomogram between predicted and observed 1-, 3- and 5-year OS in the TCGA_LUAD cohort.