Research Paper Volume 15, Issue 22 pp 12749—12762

Nectandrin B significantly increases the lifespan of Drosophila - Nectandrin B for longevity

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Figure 5. NecB inhibited age-related neurodegeneration in D. melanogaster’s brain morphology. Ctrl represents standard cornmeal medium; Rap-50 represents cornmeal medium supplemented with Rapamycin at 50 μg/mL; Rap-200 represents cornmeal medium supplemented with Rapamycin at 200 μg/mL; NecB-50 represents cornmeal medium supplemented with NecB at 50 μg/mL; and NecB-200 represents cornmeal medium supplemented with NecB at 200 μg/mL (Supplementary Table 1). A histological analysis was performed by H&E staining to examine the neurodegeneration of the Drosophila brains at the 90th days post-eclosion. n = 100; scale bars: 100 μm.