Research Paper Volume 16, Issue 5 pp 4138—4148

Azilsartan improves urinary albumin excretion in hypertension mice

class="figure-viewer-img"

Figure 6. Azilsartan ameliorates ANG/HS-induced increase in endothelial monolayer permeability in human renal glomerular endothelial cells (HrGECs). HrGEC monolayer was treated with ANG/HS with or without Azilsartan (2.5, 5 μM) for 24 hours. (A) Fluorescence intensity of FITC-dextran; (B) Trans-endothelial electrical resistance (TEER) was assayed; (C) mRNA of occludin; (D) Protein levels of occludin (n=5, ^^, P<0.01 vs. vehicle group; *, **, P<0.05, 0.01 vs. ANG/HS group).