Research Paper Volume 15, Issue 24 pp 14764—14790
Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement
Figure 5. The chemical structure of Janus kinase 3 (JAK3). (A) Initial crystal structure of JAK3 with active binding sphere addition. (B) Macromolecule with surface binding region surrounded, red indicated positive charge and blue indicated negative charge. (C) The Ramachandran chart of JAK3 macromolecule. (D) Docking structure model of FM-381-JAK3 complex.