Research Paper Volume 15, Issue 24 pp 14985—14995
Does enhanced cognitive performance reduce fracture risk? a Mendelian randomization study
Figure 1. Impact of cognitive performance on site-specific fractures. Using a two-sample Mendelian Randomization framework, we showed a causal relationship between cognitive performance and site-specific fracture risk, supporting the existence of a bone-brain axis. The IVW estimate (brown line) is significant (P < 0.05). The red box highlights the aspect of cognitive performance that significantly affects fracture incidence.