Research Paper Volume 15, Issue 24 pp 15324—15339
Parvalbumin interneurons dysfunction is potentially associated with FαMNs decrease and NRG1-ErbB4 signaling inhibition in spinal cord in amyotrophic lateral sclerosis
Figure 7. Recombinant NRG1 enhanced the motor function of ALS mice. We used the highest dose of NRG1 (0.5 mg/kg) and evaluated the motor function. (A) The weight of the ALS mice. (B) The latency time of rotarod test. *P < 0.05. In all experiments, half male and half female mice were in each group (n = 6).