Research Paper Volume 16, Issue 2 pp 1077—1095
Establishing the role of BRCA1 in the diagnosis, prognosis and immune infiltrates of breast invasive cancer by bioinformatics analysis and experimental validation
Figure 8. Correlation between BRCA1 level and immune cells infiltration in BRCA. (A) Correlation between BRCA1 expression and 24 types of immune cells. (B–E) Comparison of immune infiltration levels of immune cells (including macrophages, NK cells, pDC, and CD8+ T cells) between high and low BRCA1 level groups. (F–I) The expression of BRCA1 was negatively correlated with the level of infiltrating immune cells, including CD8+ T cells, NK cells, macrophages, and pDC. P-values were calculated with two-tailed unpaired Student’s t-test, *p < 0.05, **p < 0.01, ***p < 0.001.