Research Paper Volume 16, Issue 2 pp 1192—1217

Gut microbial community and fecal metabolomic signatures in different types of osteoporosis animal models

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Figure 2. (A) Trabecular bone at distal femoral metaphysis observed by H&E staining. (B, C) Serum levels of bone turnover biomarkers including PINP and CTX-I. (DG) Comparison of three-point bending test parameters including maximum displacement, fracture load, peak load, and stiffness. Data are means ± SEM. n = 6, *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001; ns, no significance.