Research Paper Volume 16, Issue 3 pp 2362—2384
Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition
Figure 4. PRPM mediates the MAPK signaling pathway in NAFLD. (A) IHC staining of P38, phosphorylated P38, ERK1/2 and phosphorylated ERK1/2 in NAFLD mouse models, ×200, ×400. (B–E) Correlation analysis of H-scores of P38, phosphorylated P38, ERK1/2 and phosphorylated ERK1/2. (F) Representative Western blot of P38, phosphorylated P38, ERK1/2 and phosphorylated ERK1/2. (G–J) Western blot analysis. *indicates comparison with NC, P < 0.05. #indicates a comparison with NAFLD, P < 0.05. The white line indicates 50 μm.