Research Paper Volume 16, Issue 5 pp 4169—4190
RAB22A as a predictor of exosome secretion in the progression and relapse of multiple myeloma
Figure 11. Effects of regulating RAB22A on exosomes secretion and cell proliferation. (A) Verification of exosomes by western blotting. (B) The exosomes of MSCs in control group and down-regulated RAB22A group were co-cultured with MM cell line, and the OD values of MM cells at different time points were detected by CCK-8 method. (C) The exosomes of control group and down-regulated RAB22A group were collected and stained with PKH26. The stained exosomes were co-cultured with MM cells, and the endocytosis of exosomes was observed under fluorescence microscope.