Research Paper Volume 16, Issue 5 pp 4191—4203

Calycosin (CA) inhibits proliferation, migration and invasion by suppression of CXCL10 signaling pathway in glioma

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Figure 1. CXCL10 is upregulated in glioma tissues and positively associated with tumor progression and poor prognosis. (A) Statistical evaluation of CXCL10 expression across different grades of glioma in the TCGA database. (B) analysis of CXCL10 expression in GBM tumor tissues compared to normal brain tissues using data from the TCGA database. (C) Survival curves showing the overall survival (OS) stratified by CXCL10 expression levels in glioma patients, based on TCGA data. (D, E) Comparative analysis of CXCL10 expression in 24 paired tumor and peritumor tissues from glioma patients. (F, G) examination of CXCL10 expression in GBM tumor tissues compared to normal brain tissues in 24 glioma cases. (H) OS analysis in a cohort of 24 glioma patients stratified by CXCL10 expression.