Research Paper Volume 16, Issue 5 pp 4282—4298

Figure 2. MRS voxel positions for mild WMH (A) and moderate to severe WMH participants (B). The bar color reflects the degree of overlap between individual voxels; the brighter the color, the higher the overlap. The coordinates for the transverse, coronal, and sagittal planes of the ACC are (90 90 158), while those for the PCC are (109 92 92). (C) GannetLoad output showing spectra pre (red line) and post (blue line) frequency and phase correction. (D) GannetFit output showing fitted GABA+/Cr and Glx/Cr signals: blue line, experimental data; red line, fitted data; black line, residual data. Abbreviations: ACC: anterior cingulate cortex; PCC: posterior cingulate cortex.