Research Paper Volume 16, Issue 5 pp 4327—4347

4-Hydroxyphenylpyruvate Dioxygenase-Like predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis

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Figure 2. Basic information of HPDL. (A) The level of HPDL expression between tumor and normal tissues in each type of cancer based on the integrated data from TCGA and GTEx datasets. (B) Analysis of HPDL change frequency in pan-cancer research according to cBioPortal database. (C) The HPDL expression levels between HPDL-deletion and diploid OV patients. (D) The immunofluorescence images of HPDL protein, nucleus, endoplasmic reticulum (ER), microtubules and the incorporative images in MCF7, U20S, and CAC02 cell lines. (E) The protein-protein interaction (PPI) network presents the proteins interacting with HPDL. ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05, nsP > 0.05.