Research Paper Volume 16, Issue 5 pp 4445—4468

Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma

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Figure 4. Correlation between FIGN expression and immune cell infiltration in HCC patients. (A) Correlation between the expression of FIGN and immune infiltrating cells in HCC. (B) Association between FIGN copy number variation (CNV) and B cell, CD4+ T cell, macrophages, neutrophils and dendritic cell in HC Comparison between multiple groups using analysis of variance. C. (C) Immune landscape variations between low- or high- FIGN expression groups based on CIBERSORT algorithms. (D) Correlation among infiltration levels of 22 immune cell types and FIGN expression profiles by Spearman’s analysis. *P < 0.05, **P < 0.01, ***P < 0.001, ns, no significance.