Research Paper Volume 16, Issue 5 pp 4445—4468

Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma

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Figure 5. Correlations of FIGN expression with immunotherapy related genes in HCC. (A) Expression patterns of 29 immune cell subtypes in TumorPurity, ESTIMATEScore, ImmuneScore, and StromalScore between high- and low-FIGN expression groups in HCC tumor samples. (B) Correlation between FIGN expression and dendritic cells resting, macrophage M0, T cell CD4 memory resting, mast cell resting, macrophages M2 and NK cell activated. (C) Correlation between FIGN expression and TumorPurity, ESTIMATEScore, ImmuneScore, StromalScore. (D) Correlation between FIGN and immune cell markers include CD19, CD79A and MS4A1 of B cell; B3GAT1, CD7 and KIR3DL1 of nature killer cell; CCR1, CCR5 and IL12RB1 of Th1 cell; CCR4, CCR8 and HAVCR1 of Th2 cell.