Research Paper Volume 16, Issue 5 pp 4445—4468

Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma

class="figure-viewer-img"

Figure 6. Correlations of FIGN expression with immune checkpoint genes in HCC. (A) Heatmap demonstrated the differences of FIGN and immune checkpoint genes. (B) Correlations between FIGN and the immunotherapy related genes expression, including CD40LG, CD160, CD40, CD86, TNFSF18 and TNFRSF9. (C) The differential expression of immunotherapy related genes between high- and low-FIGN expression groups in HCC samples. (D) Kaplan-Meier plot of TNFSF4, CD28, CD27, CD244, PDCD1LG2, CD86, NRP1 and CD48. The two groups were compared using t-tests. *P < 0.05, **P < 0.01, ***P < 0.001, ns, no significance.