Research Paper Volume 16, Issue 5 pp 4445—4468
Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma
Figure 7. FIGN expression predicted the responsiveness of HCC to immunotherapy, chemotherapy, and potential small-molecule compounds. Box-plots show the differences in CD8 (A) and CD274 (B) score between the low- and high-FIGN expression groups. Box-plots show the differences in Exclusion score (C), MDSC score (D), and TIDE score (E) between the low- and high-FIGN expression groups. (F) Correlation between TIDE score and FIGN expression. (G) The association between IPS and the expression of FIGN based on TCIA database. (H) Relationships between FIGN expression and chemotherapeutic sensitivity of HCC. (I) Potential small-molecule compounds might function in HCC treatment. The two groups were compared using t-tests. *P < 0.05, **P < 0.01, ***P < 0.001, ns, no significance.