Research Paper Volume 16, Issue 5 pp 4095—4115

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet

class="figure-viewer-img"

Figure 1. Aging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E) TG, (F) HDL, and (G) LDL levels in the serum of HFD-fed aged rats (each n = 6). Results of one-factor ANOVA: *p < 0.05, **p < 0.01 vs. young rats; #p < 0.05 vs. old rats.