Research Paper Volume 16, Issue 5 pp 4563—4578

Machine learning-based endoplasmic reticulum-related diagnostic biomarker and immune microenvironment landscape for osteoarthritis

class="figure-viewer-img"

Figure 4. Feature ERRGs biomarkers identification using LASSO and RF machine learning algorithm. (A) LASSO algorithm for selecting feature ERRGs related biomarkers. (B) The importance ranking of 10 pivotal DE-ERRGs via RF algorithm. (C) Identification of feature ERRGs biomarkers via RF and LASSO machine learning algorithms. (D) Pearson correlation analysis of HSPA5, UBL4A, ATF4 and PPP1R15A.