Research Paper Volume 16, Issue 5 pp 4591—4608
GBA3 promotes fatty acid oxidation and alleviates non-alcoholic fatty liver by increasing CPT2 transcription
Figure 4. GBA3 protected rats from NAFLD. (A) Successful supplementation of GBA3 in the liver of mice was confirmed through PCR and immunohistochemistry. P-value was calculated by 2-tailed Student’s t test (***, P < 0.001). (B) H&E staining of livers. (C) Oil Red O staining was used to assess lipid content. (D) Relative levels of free fatty acid, triglyceride, cholesterol, inflammatory factors, ALT, AST and LDH were detected in livers, P-value was calculated by 2-tailed Student’s t test (*, P < 0.05; **, P < 0.01; ***, P < 0.001).