Research Paper Volume 16, Issue 5 pp 4736—4758
Investigating the mechanisms of drug resistance and prognosis in ovarian cancer using single-cell RNA sequencing and bulk RNA sequencing
Figure 9. Independent prognostic analysis. (A) Seven differentially expressed genes associated with prognosis. (B) Distribution of LASSO analysis coefficient spectrum for six prognostic genes. (C) Parameter selection in the optimal cross-validation LASSO regression. (D) Patients categorized into high- and low-risk groups based on their risk scores. (E) Distribution of patients in the high- and low-risk groups. (F) Heatmap showing the distribution of prognosis-related genes. (G) Cofe values of prognosis-related genes. (H) Kaplan-Meier survival analysis curves for high- and low-risk groups. (I) Time-dependent ROC curves with area under the curve (AUC) values of 0.61, 0.58, and 0.63 for 1-year, 3-year, and 5-year intervals. (J–P) Correlation analysis of genes with risk scores and overall survival (OS).