Research Paper Volume 16, Issue 5 pp 4759—4777

Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition

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Figure 9. Mechanism diagram. β-sitosterol inhibits the binding of MK3 to IκB, reduces the activation of MK3 and IκB, promotes HSC apoptosis, and alleviates liver fibrosis.