Research Paper Volume 16, Issue 5 pp 4789—4810
SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization
Figure 2. Enrichment analysis of SORBS1 functional network and immune cell ratio analysis in BRCA. (* p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001). (A) Genes highly related to SORBS1 were identified in the BRCA cohort by Pearson test. (B) The heat map shows the top 50 genes positively related to SORBS1 in the BRCA cohort. (C) The varied proportions of 24 types of immune cells in high and low SORBS1 expression groups in tumor samples. (D) Enrichment of KEGG terms for genes related to SORBS1.