Research Paper Volume 16, Issue 5 pp 4789—4810

Figure 3. SORBS1 inhibits proliferation of MDA-MB-231 and SKBR3 cells. MDA-MB-231 and SKBR3 cells were transfected with SORBS1 overexpression plasmid and siRNA for 48 h. (A) Changes in cell viability of MDA-MB-231 and SKBR3 cells were detected by CCK8, and (B) changes in proliferative capacity of MDA-MB-231 and SKBR3 cells after 48 h of transfection were detected by clone formation assay (the CCK8 experiment counted the experimental results for 72 h, ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001, ^**** P < 0.0001).