Research Paper Volume 16, Issue 5 pp 4832—4840

Chlorogenic acid prevents ovariectomized-induced bone loss by facilitating osteoblast functions and suppressing osteoclast formation

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Figure 2. Chlorogenic acid inhibits osteoclastogenesis. (A) RAW264.7 cells were treated indicated concentration of chlorogenic acid for 2 days, the cell viability was examined by MTT assay. (B) TRAP staining and osteoclast number after treating RAW264.7 cells with RANKL and chlorogenic acid for 7 days. *p < 0.05 vs. control group.