Research Paper Volume 16, Issue 5 pp 4841—4861

HOXC9 characterizes a suppressive tumor immune microenvironment and integration with multiple immune biomarkers predicts response to PD-1 blockade plus chemotherapy in lung adenocarcinoma

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Figure 2. The correlation analysis between HOXC9 level and suppressive immune cells among cancers. (A) HOXC9 was significantly related to MDSC in LUAD. (B) HOXC9 was significantly related to Tregs in LUAD. (C) patients with high HOXC9 possessing lower DC and Tcm infiltrations. (D) HOXC9 expression was related to shorter OS of bladder cancer. (E) kidney cancer. and (F) melanoma treated with ICIs. (*P<0.05, **P<0.01, ***P<0.001).