Research Paper Volume 16, Issue 5 pp 4841—4861

HOXC9 characterizes a suppressive tumor immune microenvironment and integration with multiple immune biomarkers predicts response to PD-1 blockade plus chemotherapy in lung adenocarcinoma

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Figure 5. Hoxc9 knockdown inhibited the migration and invasion of tumor cells. (A) Remaining length of wound of CMT167 under knockdown of Hoxc9 was significantly longer compared to control (200 μm). (B) Remaining length of wound of LLC under knockdown of Hoxc9 was significantly longer compared to control (200 μm). (C, D) The statistical analysis of above assays. (EG) Count of migrated CMT167 and LCC cells was significantly decreased after knockdown of Hoxc9. (*P<0.05, **P<0.01, ***P<0.001) (100 μm).