Research Paper Volume 16, Issue 8 pp 6954—6989

Identification of a robust biomarker LAPTM4A for glioma based on comprehensive computational biology and experimental verification

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Figure 1. Identification of the key gene modules in WGCNA. (A) The volcano map showed differentially expressed genes. (B) Determination of the soft-thresholding power. (C) Dendrogram of differentially expressed genes clustered based on a dissimilarity measure (1-TOM). (D) The correlation of gene modules with clinical traits. (E) Gene correlation scatter plot of the turquoise module. (F) The 1-, 3-, and 5-years ROC for the top ten genes. (G) Comparison of the clinical significance of LAPTM4A and RP2.