Research Paper Volume 16, Issue 8 pp 7073—7100

Comprehensive characterization of β-alanine metabolism-related genes in HCC identified a novel prognostic signature related to clinical outcomes

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Figure 1. Pan-cancer analysis of 22 βAMRGs. (A) The frequency of CNV gains and losses was analyzed for the 22 βAMRGs across 20 different types of human cancers. The length of the line represents the variation frequency of the βAMRGs in pan-cancers. (B) The expression characteristics of the 22 βAMRGs were examined in 20 different types of human cancers, showing statistical significance (P < 0.05). (C, D) Heatmap and waterfall diagram were utilized to depict the SNV data of the 22 βAMRGs in pan-cancers. (E) Survival landscape analysis was conducted for the 22 βAMRGs across 20 different types of human cancers. Genes with P > 0.05 are represented by the white color, while red and blue colors indicate risk and protective genes, respectively. (F) The DNA methylation patterns of the 22 βAMRGs were examined in 20 different types of human cancers. The color gradient from orange to green signifies high to low methylation levels.