Research Paper Volume 16, Issue 8 pp 7293—7310
A novel prognostic signature based on cancer stemness and metabolism-related genes for cervical squamous cell carcinoma and endocervical adenocarcinoma
Figure 2. Screening of candidate genes based on TCGA-CESC. (A) Overview of the association between known clinical and molecular features and mRNAsi in CESC. The list shows the samples sorted by mRNAsi from low to high. Rows represent known clinical and molecular characteristics. (B) The K-M plot showed the OS of CESC patients with high or low mRNAsi. (C) The heat map of differentially expressed genes grouped according to the level of mRNAsi. (D) The volcano map of differentially expressed genes grouped according to the level of mRNAsi. (E) Different modules obtained by WGCNA clustering. (F) Cluster Heatmap showed the correlation and significant difference between gene module and mRNAsi score. The p-value is shown in parentheses. (G, H). Venn diagram of the intersection of genes in green and darkorange2 modules with metabolism-related genes (MRGS) and differentially expressed genes, respectively.