Research Paper Volume 16, Issue 8 pp 7437—7447

Figure 5. Correlations between NOX4 expression and immune cell infiltration levels. (A) A heatmap displays the correlations between NOX4 expression and infiltration levels of six immune cell types in TCGA cohorts. (B) Another heatmap depicts the correlations between NOX4 expression and infiltration levels of three immunosuppressive cell types in TCGA cohorts. (C) A bar plot compares the biomarker relevance of NOX4 with standardized cancer immune evasion biomarkers in immune checkpoint blockade (ICB) subcohorts, including cancer-associated fibroblasts (CAFs), myeloid-derived suppressor cells (MDSCs), and regulatory T cells (Tregs); (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).