ࡱ> QS  !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPTRoot Entry F@RWorkbookڜSummaryInformation(DocumentSummaryInformation8 \ppriyaKrasnova Ba==h,x< 8X@"1̊Calibri1Calibri1Calibri1Calibri1Calibri1@Calibri1Calibri1Calibri1hCalibri1̊Calibri1h8Cambria1,8Calibri18Calibri18Calibri1Calibri1Calibri1<Calibri1>Calibri1?Calibri14Calibri14Calibri1 Calibri1 Calibri1Calibri1 Calibri"$"#,##0_);\("$"#,##0\)!"$"#,##0_);[Red]\("$"#,##0\)""$"#,##0.00_);\("$"#,##0.00\)'""$"#,##0.00_);[Red]\("$"#,##0.00\)7*2_("$"* #,##0_);_("$"* \(#,##0\);_("$"* "-"_);_(@_).))_(* #,##0_);_(* \(#,##0\);_(* "-"_);_(@_)?,:_("$"* #,##0.00_);_("$"* \(#,##0.00\);_("$"* "-"??_);_(@_)6+1_(* #,##0.00_);_(* \(#,##0.00\);_(* "-"??_);_(@_)                                                                       ff  +  )  ,  *     P  P        `            a>   @  8 "x@ @  "8@ @  "8@ @      8  h@ @  !0@ @   @ @  !0@ @   h@ @  !0   !0@ @   h@ @  !0@ @   @ @  !0@ @  ||Q_Vr}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-} 00\);_(*}-}  00\);_(*}-}  00\);_(*}-}  00\);_(*}-}  00\);_(*}-}  00\);_(*}-} 00\);_(*}-} 00\);_(*}-}> 00\);_(*}-}? 00\);_(*}}@}}A}}B}-}C 00\);_(*}-}D 00\);_(*}-}E 00\);_(*}-}F 00\);_(*}-}G 00\);_(*}-}H 00\);_(*}-}I 00\);_(*}-}J 00\);_(*}-}K 00\);_(*}-}L 00\);_(*}-}M 00\);_(*}-}N 00\);_(*}-}O 00\);_(*}-}P 00\);_(*}-}+ 00\);_(*}-}, 00\);_(*}-}- 00\);_(*}-}. 00\);_(*}-}: 00\);_(*}-}; 00\);_(*}A}1 00\);_(*;_(@_) }A}2 00\);_(*?;_(@_) }A}3 00\);_(*23;_(@_) }-}4 00\);_(*}A}0 a00\);_(*;_(@_) }A}( 00\);_(*;_(@_) }A}7 e00\);_(*;_(@_) }}5 ??v00\);_(*̙;_(@_)    }}9 ???00\);_(*;_(@_) ??? ??? ??? ???}}) }00\);_(*;_(@_)    }A}6 }00\);_(*;_(@_) }}* 00\);_(*;_(@_) ??? ??? ??? ???}-}= 00\);_(*}}8 00\);_(*;_(@_)    }-}/ 00\);_(*}U}< 00\);_(*;_(@_)  }A}" 00\);_(*;_(@_) }A} 00\);_(*ef;_(@_) }A} 00\);_(*L;_(@_) }A} 00\);_(*23;_(@_) }A}# 00\);_(*;_(@_) }A} 00\);_(*ef;_(@_) }A} 00\);_(*L;_(@_) }A} 00\);_(*23;_(@_) }A}$ 00\);_(*;_(@_) }A} 00\);_(*ef;_(@_) }A} 00\);_(*L;_(@_) }A} 00\);_(*23;_(@_) }A}% 00\);_(*;_(@_) }A} 00\);_(*ef;_(@_) }A} 00\);_(*L;_(@_) }A} 00\);_(*23;_(@_) }A}& 00\);_(*;_(@_) }A} 00\);_(*ef;_(@_) }A} 00\);_(*L;_(@_) }A}  00\);_(*23;_(@_) }A}' 00\);_(* ;_(@_) }A} 00\);_(*ef ;_(@_) }A} 00\);_(*L ;_(@_) }A}! 00\);_(*23 ;_(@_) 4   !4   ! 20% - Accent1M 20% - Accent1 ef % 20% - Accent2M" 20% - Accent2 ef % 20% - Accent3M& 20% - Accent3 ef % 20% - Accent4M* 20% - Accent4 ef % 20% - Accent5M. 20% - Accent5 ef % 20% - Accent6M2 20% - Accent6  ef % 40% - Accent1M 40% - Accent1 L % 40% - Accent2M# 40% - Accent2 L湸 % 40% - Accent3M' 40% - Accent3 L % 40% - Accent4M+ 40% - Accent4 L % 40% - Accent5M/ 40% - Accent5 L % 40% - Accent6M3 40% - Accent6  Lմ % 60% - Accent1M 60% - Accent1 23 % 60% - Accent2M$ 60% - Accent2 23ٗ % 60% - Accent3M( 60% - Accent3 23֚ % 60% - Accent4M, 60% - Accent4 23 % 60% - Accent5M0 60% - Accent5 23 %! 60% - Accent6M4 60% - Accent6  23 % "Accent1AAccent1 O % #Accent2A!Accent2 PM % $Accent3A%Accent3 Y % %Accent4A)Accent4 d % &Accent5A-Accent5 K % 'Accent6A1Accent6  F %(Bad9Bad  %) Calculation Calculation  }% * Check Cell Check Cell  %????????? ???+ Comma,( Comma [0]-&Currency.. Currency [0]/Explanatory TextG5Explanatory Text % 0Good;Good  a%1 Heading 1G Heading 1 I}%O2 Heading 2G Heading 2 I}%?3 Heading 3G Heading 3 I}%234 Heading 49 Heading 4 I}% 5InputuInput ̙ ??v% 6 Linked CellK Linked Cell }% 7NeutralANeutral  e%3Normal % 8Noteb Note   9OutputwOutput  ???%????????? ???:$Percent ;Title1Title I}% <TotalMTotal %OO= Warning Text? Warning Text %XTableStyleMedium9PivotStyleLight16`@Suppl. Table 1} - Gene nameESR2Bisulphite sequencingBTG1DNA microarrayBTG2IGFBP6LOXL2NR4A3PHLDA1STACTERTFlow cytometryDNAJA3Genetic screenH2AFXImmunofluorescenceHIRAHMGA2 SERPINB5SUZ12BCL2MAPK1ImmunohistochemistryASF1AKnockoutATMBACH1BUB1BCDK2CDKN1ACHD5CHEK1CHEK2CTSKDDB2EGR1ERCC1ERCC4EWSR1G6PD GADD45AGCLMGPX1HELLSIL1AJDP2JUNDKCNJ12LIG4LMNB1MAP2K7MAPKAPK5NFE2L2POU1F1PPP1R15APRDX2PTENRBP2RUVBL2S100A6SKP2SP100 STK11SUPT5HTACC3TERF1TERF2TOP1TP53BP1TP63WRNWT1XRCC5YBX1ZMPSTE24ZNF148AGTKnockout or overexpressionBMI1C2orf40CEBPBCPEB1GJA1GNG11IGFBP5ING2 NUAK1PLA2R1RAC1RNASELRSL1D1SIN3BTGFB1I1TNFSF15TXNIPCD28Loss of expressionBRCA1 MutationsBRCA2DHCR24DKC1NFYAPER2PCNANorthernRAB27BHSPA1AAGTRAPOverexpressionALOX15BARID3AATRAURKABHLHB2BRAFCBX8CCND1CDK4CDK6CDKN1BCDKN1CCDKN2ACDKN2AIPCDKN2BCLU CXCL1CYR61DEKE2F1EHFEIF4EETS1ETS2FBXO31FGFR3 FOSGNL3HEPACAMHRASHSPA9BICAM1ID1IFNGIGF1IL15IL8ILKING1IRF3IRF5IRF7LEO1MAP2K1MAP2K2MAP2K6MDM2MORC3MORF4MOSMST1RMXD4MYCNEK6NINJ1NOX4NPM1OCLNOTX2PCGF2PDZD2PEX19PIAS4PIM1PMLPNPT1PPM1DPRPF19PTTG1RAF1RPLP1RPS6KA6RUNX1SFNSIRT1SKILSLC13A3SMARCB1SMURF2SOX5SP1SPIN1SRCSREBF1STAT5B STUB1SYKTADA3TAGLNTBX2TGFA TMPRSS11ATP53TP73VEGFAYPEL3ZFP36ABI3BPRNA interferenceBCL6BLVRACAV1CBX7CENPACSNK2A1DUSP3ENDOGFOXM1FOXO3GLB1HIVEP1IGFBP3ITGB4KIAA1524KLMARCH5MECP2MMP9PBRM1POT1PPP1CAPRKCDPSMD14RBX1SENP1SENP2SENP7SERPINE1SMARCA4SOCS1SOD1TBX3TCEB3TNFSF13TXNVHLWNT16WNT2BRD7"RNA interference or overexpressionHSPB2EZH2IL1BIL1RNLMNAPSAPRB1SHC1TGFB1CASP3IGFBP1IGFBP2ANGPT1 Stimulation with ANGPT1 BMP4Stimulation with BMP4FGF1Stimulation with FGF1FGF2Stimulation with FGF2IGFBP7Stimulation with IGFBP7IFNB1 Stimulation with interferon betaKRASStimulation with KRASPLA2G2AStimulation with PLA2G2ASERTAD1Stimulation with SERTAD1 TGFB2Stimulation with TGFB2WNT3AStimulation with WNT3AMMP2MRE11ACD82Yeast two-hybrid screenHGNC ID PubMed ID Northern blot Western blotNorthern blot, Western blotImmunofluorescence qPCRqPCR, Caspase activity assayqPCR, Western blotqPCR ,Western blotMethod/Observation3Supplementary Table 1. List of CS-associated genes.23 -4g445WZ555 6Z_666.:7t778OZ888 9BH99997<:v{::;@G;;;<B`<<!=[ = )>c > ccB  43HR[eZo"yz"  dMbP?_*+%,&ffffff?'ffffff?(?)?M"HP LaserJet P1005D dXXHP LaserJet P1005  ld'4@ @ dd@ " dXX333333?333333?&<3U} m>} m } "}  Column A;C,,,,,,, , , , , ,,,,,,,,,,,,,,,,,,, D, ?? @ A! A+ B" E~ F@@ G~ HX IM~ Jt@ KN~ Lv Im~ Jq@ Kn~ L Io~ J {@ Kn~ L I~ J@~@ K~ La Ip~ J@ Kn~ L I~ J@ K~ L^v I~ J؈@ K~ L\8 Iq~ J@ Kn~ LY Ir~ J@@ Kn~ Lda I~ J8@ K~ L I~ J@ K&~ Lf I~ JH@ K~ L0 Is~ JX@ Kn~ L)L I~ J@ K~ L IO~ J@ KN~ L I ~ J@ K ~ L It~ J$@ Kn~ Lo Ib~ J0@ Kc~ L6h Id~ J4@ Kc~ LzP I~ J@ K~ L I~ J@ K~ LbO I~ J@ K~ LbO I~ J@ K~ LB IP~ J@ KN~ L^ I~ J@ K(~ L2 I~ Jܗ@ K~ Lz I~ JT@ K~ L} Iu~ J-@ Kn~ L! 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