ࡱ>  bjbj 2vgvg# x x     8V4Dg%b$d$d$d$d$d$d$$c'*($ $  4!%j"j"j"   b$j"b$j"j"""!Y""N$7%0g%"A+nA+"A+ "|j"$$"Xg%A+x X : @Supplementary Material 1. List of excluded references and reasons for exclusion. NO.ReferencesReason1Li L, Wang A, Wang J, Wang Y, Y J. Value of high-b-value Diffusion-weighted Imaging in the Differential Diagnosis of Prostate Cancer and Prostatitis. Chin J Med Imaging.2012 12: 887-889.Sample size<302Colvin SD, Cason DE, Galgano SJ, Triche BL, Gordetsky J, Rais BS, et al. Fusion of high B-value diffusion-weighted and T2-weighted MR images increases sensitivity for identification of extraprostatic disease in prostate cancer. Clin Imag. (2020) 68.bpMRI3Li X. Application value of high B value DWI scan combined with dynamic contrast-enhanced MRI in diagnosis of prostate cancer. China Modern Pharmacy. (2019) 13: 61-62.bpMRI4Zhou J, Meng Y, Xu M. Application of high B value diffusion weighted imaging in the diagnosis of prostate cancer. J Med Theor&Prac. (2016) 29: 2974-2976.Sample size<305Tom S, Keith G, Paul M. Inter-observer agreement of prostate cancer in high b-value diffusion weighted imaging with small and large field-of-view. Clin Radiol. (2016) 71.Unrelated topic6Agarwal HK, Mertan FV, Sankineni S, Bernardo M, Senegas J, Keupp J, et al. Optimal high b-value for diffusion weighted MRI in diagnosing high risk prostate cancers in the peripheral zone. Journal of magnetic resonance imaging : JMRI. (2017) 45.Non high b value7Andrew BR, Nainesh P, Andrea SK, Max XK, James SB, Samir ST, et al. Prostate Cancer Detection Using Computed Very High b-value Diffusion-weighted Imaging: How High Should We Go? Acad Radiol. (2016) 23.Review8Rosenkrantz AB, Parikh N, Kierans AS, Kong MX, Babb JS, Taneja SS, et al. Prostate Cancer Detection Using Computed Very High b-value Diffusion-weighted Imaging: How High Should We Go? Acad Radiol. (2016) 23.Duplicates9Rosenkrantz AB, Mannelli L, Kong X, Niver BE, Berkman DS, Babb JS, et al. Prostate cancer: utility of fusion of T2-weighted and high b-value diffusion-weighted images for peripheral zone tumor detection and localization. Journal of magnetic resonance imaging : JMRI. (2011) 34.Review10Liu J, Zhang H. High b -values of diffusion -weighted MR Imaging in diagnosis of prostate cancerous and non-cancerous regions by GE3.0T. China Modern Med. (2011) 18: 9-10.No data for analysis11S. Jendoubi M. Wagner S. Montagne et al. MRI in the diagnosis of prostate cancer: whether the calculated high B value DWI can replace the self-collected DWI. Inter J Med Radiology,2019,42(06):749-50.Abstract12Roshan AK, Joshua K, Tyler MS, et al. Relationship between kurtosis and bi-exponential characterization of high b-value diffusion-weighted imaging: application to prostate cancer. Acta Radiologica 2018; 59.No useful data13Boesen L, Norgaard N, Logager V, Balslev I, Bisbjerg R, Thestrup KC, et al. Assessment of the Diagnostic Accuracy of Biparametric Magnetic Resonance Imaging for Prostate Cancer in Biopsy-Naive Men: The Biparametric MRI for Detection of Prostate Cancer (BIDOC) Study. JAMA Netw Open. (2018) 1: e180219. doi:10.1001/jamanetworkopen.2018.0219biparametric14Boesen L, Norgaard N, Logager V, Balslev I, Bisbjerg R, Thestrup KC, et al. Prebiopsy Biparametric Magnetic Resonance Imaging Combined with Prostate-specific Antigen Density in Detecting and Ruling out Gleason 7-10 Prostate Cancer in Biopsy-naive Men. Eur Urol Oncol. (2019) 2: 311-319. doi:10.1016/j.euo.2018.09.001Duplicates15Rais-Bahrami S, Siddiqui MM, Vourganti S, Turkbey B, Rastinehad AR, Stamatakis L, et al. Diagnostic value of biparametric magnetic resonance imaging (MRI) as an adjunct to prostate-specific antigen (PSA)-based detection of prostate cancer in men without prior biopsies. Bju Int. (2015) 115: 381-388. doi:10.1111/bju.12639biparametric16Y. Zhang S. A. Wells B. L. Triche. Stimulated -echo diffusion -weighted imaging with moderate b values for the detection of prostate cancer. Inter J Med Radiology,2020,43(04):501.Abstract17Jie Ceng Longlin Yin Ju Sun. Study on the Application Value of IVIM Imaging with Different b Value Combinations in the Diagnosis of Prostate Cancer. J Clin Radiology. 2020,39(07):1367-1372.(in Chinese)Non-high b value18Xiaoxue Ye Chongyong Xu Yongfei Zhou. Study on the Application Value of IVIM Imaging with Different b Value Combinations in the Diagnosis of Prostate Cancer.,2020,27(14):1671-1674.(in Chinese)Duplicates19Jambor I, Bostrom PJ, Taimen P, Syvanen K, Kahkonen E, Kallajoki M, et al. Novel biparametric MRI and targeted biopsy improves risk stratification in men with a clinical suspicion of prostate cancer (IMPROD Trial). J Magn Reson Imaging. (2017) 46: 1089-1095. doi:10.1002/jmri.25641biparametric20Hamed K, Ravi TS, Elisabeth W, Berthold K, Marcel DN, Thitinan C, et al. Image quality and diagnostic accuracy of complex-averaged high b value images in diffusion-weighted MRI of prostate cancer. Abdom Radiol. (2019) 44.duplicates21Low-to-high b value DWI ratio approaches in multiparametric MRI of the prostate: feasibility, optimal combination of b values, and comparison with ADC maps for the visual presentation of prostate cancer. Quant Imag Med Surg. (2018) 8.No data for extraction22Ma S, Xu K, Xie H, Wang H, Wang R, Zhang X, et al. Diagnostic efficacy of b value (2000 s/mm2) diffusion-weighted imaging for prostate cancer: Comparison of a reduced field of view sequence and a conventional technique. Eur J Radiol. (2018) 107.Duplicates23Shen J, Xue F, Cai Y, Lu JG, Wang J. The clinical value of ultra-high b value diffusion weighted magnetic resonance imaging combined with ultrasound elastography for the diagnosis of prostate cancer. Imaging Res Med Application. (2018) 2: 96-98.Multiparameters24Yang C, Yang Q, Dang S, Duan HF, Ma G, Duan X. Effect of Two Different Diffusion Weighted Imaging with Ultra-high b Values on Image Quality in Prostate Cancer MRI. Chin J Med Imaging. (2018) 26: 606-611.No data for extraction25Wang W, Shao ZH, Zeng JQ, Wu DL, Wang GL, Wang PJ. [Effects of different computed high b-values on diffusion weighted imaging scores in Prostate Imaging Reporting and Data System version 2 of prostate cancer in peripheral zone]. Zhonghua yi xue za zhi. (2017) 97.Duplicates26Grant KB, Agarwal HK, Shih JH, Bernardo M, Pang Y, Daar D, et al. Comparison of calculated and acquired high b value diffusion-weighted imaging in prostate cancer. Abdom Imaging. (2015) 40.No data for extraction27Kinzya BG, Harsh KA, Joanna HS, Marcelino B, Yuxi P, Dagane D, et al. Comparison of calculated and acquired high b value diffusion-weighted imaging in prostate cancer. Abdom Imaging. (2015) 40.No data for extraction28T., Metens, D., Miranda, J., Absil C., Matos What is the Optimal B Value in Diffusion-Weighted MR Imaging to Depict Prostate Cancer at 3T? Eur. Radiol. 22, (2012).No data 29Park SY, Kim CK, Park BK, Kwon GY. Comparison of apparent diffusion coefficient calculation between two-point and multipoint B value analyses in prostate cancer and benign prostate tissue at 3 T: preliminary experience. AJR. American journal of roentgenology. (2014) 203.Non-high b value30Ueno Y, Takahashi S, Ohno Y, Kitajima K, Yui M, Kassai Y, et al. Computed diffusion-weighted MRI for prostate cancer detection: the influence of the combinations of b-values. The British journal of radiology. (2015) 88.Combinations of b-values31  OPQU`ghj  $ & B D F J   $ % & ( q r ./оЯvvvvvvvvvvh~YhCJOJQJaJh~YhrCJOJQJaJh~Yh^)CJOJQJaJh_CJOJQJaJh~Yh dCJOJQJaJ"h~Yh5CJOJQJ\aJh_5CJOJQJ\aJhn*5CJOJQJ\aJ"h~Yh d5CJOJQJ\aJ.QU`g$Ifgd%Ml $Ifl $$Ifa$gdl $a$gd~Yghj& D eO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMTD F J  % eO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT% & ( eO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT r eO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd>$$IfTFV$(+V"|0+    44 lapytMT /?eO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT/>?@B67GHIK$&246<  TVfhjp<=GHIL⵵⵵⵵⵵h~Yhr:CJOJQJaJh~YhCJOJQJaJh~Yh|CJOJQJaJh~Yh^)CJOJQJaJh~YhCJOJQJaJG?@B7HeO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMTHIKeO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd`$$IfTFV$(+V"|0+    44 lapytMTeO<)$Ifgd%Ml $Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT&4eO<)$Ifgd%Ml $Ifgd|l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT46<eO<<$Ifgd|l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMTVR<)$Ifgd^)l $$Ifa$gdl kdH$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml VhjpR<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml R<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml =R<)$Ifgd^)l $$Ifa$gdl kdv $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml =HILR<)$Ifgd^)l $$Ifa$gdl kd0 $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml 468>RTZ\tvx~  !(!)!5!6!7!:!"""""#"$"'"###(#)#*#-#ĵh~Yh9CJOJQJaJh~YhCJOJQJaJh~YhCCJOJQJaJh~YhUYCJOJQJaJh~YhPCJOJQJaJh~Yhr!CJOJQJaJh~Yhr:CJOJQJaJh~Yh^)CJOJQJaJ068>R<)$Ifgd^)l $$Ifa$gdl kd $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml TR<)$IfgdPl $$Ifa$gdl kd $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml Tvx~ R<)$Ifgd^)l $$Ifa$gdl kd $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml   )!R<)$Ifgd^)l $$Ifa$gdl kdB $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml )!6!7!:!"R<)$Ifgd^)l $$Ifa$gdl kd $$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml "#"$"'"#R<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml #)#*#-##$R<)$Ifgd^)l $$Ifa$gdl kdp$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml -#$"$#$-$.$/$2$%'%(%7%8%9%<%&&&&& &"&#&'*'+'5'6'7'9':'''((((((((((((())))))))ĵĵĵĵĵh~Yhk|CJOJQJaJh~YhCJOJQJaJh~Yh?CJOJQJaJh~Yhv'CJOJQJaJh~YhtkCJOJQJaJh~Yh^)CJOJQJaJh~YhB CJOJQJaJ5#$.$/$2$(%R<)$IfgdB l $$Ifa$gdl kd*$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml (%8%9%<%&R<)$Ifgdtkl $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml && &#&+'R<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml +'6'7':''R<)$Ifgd^)l $$Ifa$gdl kdX$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml '((((R<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml (((()R<)$Ifgdk|l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml ))))*R<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml )********+++++++++++xxxxxxxxyyyyyyyyzzzzzzzz{{{{{ĩ⧘≉≉zzzh~Yh;j-CJOJQJaJh~YhgT>CJOJQJaJh~Yh7QCJOJQJaJUh~YCJOJQJaJh~Yh~YCJOJQJaJh~YheCJOJQJaJh~Yhv'CJOJQJaJh~Yh?CJOJQJaJh~YhUYCJOJQJaJ0****+R<)$Ifgd^)l $$Ifa$gdl kd@$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml ++++xR<)$Ifgd^)l $$Ifa$gdl kd$$IfTFV$(+V"|0+    44 lapytMT$Ifgd%Ml Jin TK, Sheng X, Bradford JW, Baris T, Peter LC, Peter AP, et al. Automated prostate cancer detection using T2a weighted and high b value diffusiona weighted magnetic resonance imaging. Med Phys. (2015) 42.No data32de Perrot T, Scheffler M, Boto J, Delattre BMA, Combescure C, Pusztaszeri M, et al. Diffusion in prostate cancer detection on a 3T scanner: How many b-values are needed? Journal of magnetic resonance imaging : JMRI. (2016) 44.Review33Vallini V, Ortori S, Boraschi P, Manassero F, Gabelloni M, Faggioni L, et al. Staging of pelvic lymph nodes in patients with prostate cancer: Usefulness of multiple b value SE-EPI diffusion-weighted imaging on a 3.0 T MR system. European journal of radiology open. (2016) 3.Unrelated topic34Zhang Y, Wu C, Bao M, Li H, Yan X, Liu X, et al. New RESOLVE-Based Diffusional Kurtosis Imaging in MRI-Visible Prostate Cancer: Effect of Reduced b Value on Image Quality and Diagnostic Effectiveness. AJR. American journal of roentgenology. (2016) 207.Unrelated topic35Ayumu K, Tsutomu T, Teruki S, Naoki K, Yoshiyuki M, Akira Y, et al. Incremental value of high b value diffusion-weighted magnetic resonance imaging at 3-T for prediction of extracapsular extension in patients with prostate cancer: preliminary experience. La radiologia medica. (2017) 122.No data 36Zeng J, Deng, Q, Li S, Chen S. Diagnostic value of DWI with ultrahigh b-value combined with DCE-MRI in prostate cancer. China Med,53(8):911-914Combined methods37 Mostafa A, Jean PS, Kaela G, Lucy S, Ali J, Hang Y, et al. Biparametric vs multiparametric prostate magnetic resonance imaging for the detection of prostate cancer in treatment naive patients: a diagnostic test accuracy systematic review and meta analysis. Bju Int. 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