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Warning Text %XTableStyleMedium2PivotStyleLight16`9Biomarker_LEfSe4 i Taxon name Taxon rankTaxonomyLDA effect sizep-value p-value (FDR)FMTSFMTC AY442821_gGenusDBacteria: Firmicutes: Clostridia: Clostridiales: Christensenellaceae2.446170.000000.000370.05600 PAC002521_sSpeciesPBacteria: Firmicutes: Clostridia: Clostridiales: Christensenellaceae: AY442821_g HM124337_s[Bacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae: PAC001528_g2.085320.000180.02422 PAC001583_sMBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: PAC000661_g2.145630.000010.02794 PAC001381_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001092_g2.690980.002070.10002 PAC001542_sVBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: Pseudoflavonifractor2.122890.000030.02625 EU504499_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC001067_g2.153190.000040.001530.02973 AdlercreutziaMBacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae3.503220.000050.006650.64361!Adlercreutzia equolifaciens group\Bacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: Adlercreutzia PAC002450_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC001068_g2.026290.000450.02147 ASTB_g_ucVBacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae: ASTB_g3.646770.000070.936730.05019Muribaculum_ucPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: Muribaculum4.244730.000080.000090.528604.04208 PAC001614_sOBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: Acutalibacter2.235160.000140.034670.00054 BacillalesOrderBacteria: Firmicutes: Bacilli2.192060.000150.053190.02238 AllobaculumNBacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae4.381380.000165.509330.69663 PAC000681_s[Bacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae: Allobaculum4.381065.50580PAC000197_g_ucHBacteria: Tenericutes: Mollicutes: PAC001057_o: PAC000197_f: PAC000197_g2.105690.000170.004810.02995 PAC002357_sPBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: Eubacterium_g82.139070.000500.02773PAC002514_s group2.891960.000230.208710.05296 PAC001468_g@Bacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae3.298330.000240.000250.003290.40061 PAC001731_sMBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: PAC001468_g EU474337_sZBacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: PAC001266_g2.503780.064480.00090 PAC001005_sMBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: PAC000683_g2.612340.000260.002830.08453 PAC002428_sLBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: KE159538_g3.335010.000270.435000.00264 FJ879881_sNBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: Ruminococcus2.130020.02672CoriobacteriiaClassBacteria: Actinobacteria4.371040.0003312.093087.39359Coriobacteriales(Bacteria: Actinobacteria: CoriobacteriiaCoriobacteriaceaeFamily:Bacteria: Actinobacteria: Coriobacteriia: Coriobacteriales0.00034 PAC001452_g@Bacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae2.849440.014960.15615PAC001981_s groupMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001452_gPAC002459_s groupMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC000664_g2.709030.105200.00307ActinobacteriaPhylumBacteria4.443410.0004013.041287.48958 PAC001104_s3.278840.418010.03814 KE159797_sLBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: KE159797_g2.429370.000480.000490.061620.00811Actinobacteria_c3.628450.944160.09425Bifidobacteriales*Bacteria: Actinobacteria: Actinobacteria_c3.625060.000570.000580.925900.08260Bifidobacteriaceae=Bacteria: Actinobacteria: Actinobacteria_c: BifidobacterialesBifidobacteriumQBacteria: Actinobacteria: Actinobacteria_c: Bifidobacteriales: Bifidobacteriaceae3.624970.92572"Bifidobacterium pseudolongum groupbBacteria: Actinobacteria: Actinobacteria_c: Bifidobacteriales: Bifidobacteriaceae: Bifidobacterium3.624640.92508Enterorhabdus muris\Bacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: Enterorhabdus3.630090.000810.000841.075060.22193Lactobacillus gasseri groupOBacteria: Firmicutes: Bacilli: Lactobacillales: Lactobacillaceae: Lactobacillus4.312626.153452.04546 PAC001069_s3.009080.056980.26100 HM124212_s2.560270.000880.07304 Enterorhabdus3.954380.000970.001003.093171.29279 MuribaculumCBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae4.207861.362704.59015 PAC002481_sOBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Prevotellaceae: Prevotella2.231360.000990.001020.000320.03415 PAC001117_s2.536580.001040.001070.003450.07205 EU456594_g3.529730.001150.001190.879520.20245 EU456594_sYBacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: EU456594_g DQ456215_s2.264520.001310.001360.000770.03728 PAC002302_s3.100650.001410.036710.28866 PAC000183_sQBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: Clostridium_g242.195090.001600.001660.023590.05472Pseudomonadales-Bacteria: Proteobacteria: Gammaproteobacteria2.696980.001610.001670.153430.05411 PAC001188_sOBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: Oscillibacter2.151350.042130.01399 PAC001554_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001200_g2.632630.138700.05312 PAC002348_sLBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: KE159571_g2.381530.001840.001910.052410.00449 PAC001404_s2.198690.001890.001960.000410.03177Pseudomonadaceae>Bacteria: Proteobacteria: Gammaproteobacteria: Pseudomonadales2.692880.001900.001970.152390.05400 PseudomonasPBacteria: Proteobacteria: Gammaproteobacteria: Pseudomonadales: Pseudomonadaceae PAC001122_s2.107300.002170.002270.002120.02745 PAC000664_g3.514720.002230.002330.925040.27098Lactobacillus reuteri group3.682511.655070.69247Pseudomonas fulva group]Bacteria: Proteobacteria: Gammaproteobacteria: Pseudomonadales: Pseudomonadaceae: Pseudomonas2.209850.048880.01671 PAC001679_g2.817320.002550.002660.136150.00502 PAC001679_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001679_g0.00267Pseudomonas veronii group2.422730.002620.002750.082100.02939 EU622763_s2.914210.022480.18642 GQ448612_s2.605110.002970.08093BetaproteobacteriaBacteria: Proteobacteria2.205250.003080.003230.054200.02237 PAC001120_s3.377430.485080.00834 PAC001068_s3.011370.104720.30980 PAC001112_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC001112_g2.421850.020310.07289 KE159810_g2.971600.003160.003330.001520.18866 KE159810_sLBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: KE159810_g PAC001515_s2.346510.003180.003350.045380.00117 PAC000687_g2.926040.003590.003790.183710.01523 PAC000687_s[Bacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae: PAC000687_g PAC002411_s3.517890.003600.003801.150250.49140 DQ777929_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001199_g2.598370.004190.004440.09500< 0.01590 PAC001762_g2.273570.004200.004450.017920.05525 EF096150_s[Bacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae: PAC001762_g2.277410.017360.05502 PAC001212_g2.411760.004660.004950.005320.05673Caulobacterales-Bacteria: Proteobacteria: Alphaproteobacteria2.242640.004890.005200.063470.02873Caulobacteraceae>Bacteria: Proteobacteria: Alphaproteobacteria: CaulobacteralesFaecalibaculum rodentium^Bacteria: Firmicutes: Erysipelotrichi: Erysipelotrichales: Erysipelotrichaceae: Faecalibaculum2.873680.199340.05002 Prevotella3Bacteria: Bacteroidetes: Bacteroidia: Bacteroidales2.990160.005210.034860.23018PAC001200_g_uc2.583900.005630.006030.001200.07769 AB185622_s3.422940.005680.006080.626790.09736 PAC001199_s2.098670.005700.006120.000120.02490Streptococcus danieliaeOBacteria: Firmicutes: Bacilli: Lactobacillales: Streptococcaceae: Streptococcus2.393000.006580.007080.075580.02636ParaprevotellaCBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Prevotellaceae2.585050.007430.008000.003280.08001 PAC000215_sSBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Prevotellaceae: Paraprevotella0.00801ErysipelotrichiBacteria: Firmicutes4.302570.007610.008218.325744.31169Streptococcaceae.Bacteria: Firmicutes: Bacilli: Lactobacillales2.718030.008780.009520.207480.10320 PAC001072_s3.587320.009530.408421.18152 PAC001366_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001165_g2.113180.040070.01432 EU504031_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC001472_g2.703740.009320.010130.110520.00965Muribaculaceae_uc2.944460.009890.010790.021890.19768 PAC002441_s2.575220.010070.011000.048500.12348 PAC001079_seBacteria: Proteobacteria: Deltaproteobacteria: Desulfovibrionales: Desulfovibrionaceae: Desulfovibrio4.643380.010110.0110616.179347.38094 PAC001528_s2.355940.010920.011960.070160.02499 Parvibacter2.955820.011620.012770.235200.05474 Streptococcus@Bacteria: Firmicutes: Bacilli: Lactobacillales: Streptococcaceae2.562330.012780.131330.05855Parvibacter caecicolaZBacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: Parvibacter PAC001184_sJBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: Neglecta2.746920.012790.041540.15300 PAC002449_s4.009760.441342.48661 PAC002490_s2.842790.012800.114490.25354 BrevundimonasPBacteria: Proteobacteria: Alphaproteobacteria: Caulobacterales: Caulobacteraceae2.140400.013330.014730.052860.02547 PAC001062_g2.665080.014740.128970.03668 PAC001062_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC001062_g0.01475 PAC001372_g2.906100.015250.016920.176590.01568 PAC001573_g@Bacteria: Firmicutes: Clostridia: Clostridiales: Mogibacterium_f2.356290.016930.088860.04368PAC001048_s groupMBacteria: Firmicutes: Clostridia: Clostridiales: Ruminococcaceae: PAC000672_g2.014990.016040.017850.02067 PAC001202_s2.244770.016820.018750.005930.04085Bacteroidaceae2.718340.017420.019460.093450.19781 BacteroidesCBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Bacteroidaceae0.01947 Clostridium?Bacteria: Firmicutes: Clostridia: Clostridiales: Clostridiaceae3.017860.331570.12337 Kineothrix2.444540.019480.009500.06494 LT821227_g3.433460.019491.141300.59888 PAC000197_g;Bacteria: Tenericutes: Mollicutes: PAC001057_o: PAC000197_f2.705050.019500.121980.22319 PAC001125_sLBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: Kineothrix2.446620.019510.00924 PAC001394_sYBacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: LT821227_g0.01952 PAC001786_s2.536700.019530.025770.09438 PAC002419_s2.540120.019540.050040.11918 AB626901_sHBacteria: Tenericutes: Mollicutes: PAC001057_o: PAC001057_f: PAC001109_g2.599650.018180.020420.010820.09017JRPE_scBacteria: Proteobacteria: Epsilonproteobacteria: Campylobacterales: Helicobacteraceae: Helicobacter2.232870.018210.020460.033770.06776 PAC001105_g2.172640.019030.021410.02987 PAC001105_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001105_g0.02142PAC001472_g_uc2.293700.021950.027600.06672Proteobacteria4.635610.0198518.9020210.25965 KE159797_g2.825280.022400.301810.16826Bacteroides acidifaciensPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Bacteroidaceae: Bacteroides2.643310.022410.042900.13067 KE159605_sLBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: KE159605_g3.012310.022420.107860.31341 PAC001809_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001212_g2.377550.020140.022890.004290.05179 DQ394665_s2.015530.022150.025210.090830.11136Neglecta2.740390.022560.025750.043480.15327 PAC001109_g;Bacteria: Tenericutes: Mollicutes: PAC001057_o: PAC001057_f2.947750.025780.067150.24428Alistipes inopsMBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Rikenellaceae: Alistipes3.100510.025800.098120.34999 PAC001710_s2.210040.023760.027230.033940.00173 HM124188_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC000198_g2.490500.025600.102090.16377 PAC001095_s3.262890.029410.761931.12810Deltaproteobacteria4.630210.0294218.189119.65357Desulfovibrionales-Bacteria: Proteobacteria: Deltaproteobacteria4.630170.0294318.187589.65292DesulfovibrionaceaeABacteria: Proteobacteria: Deltaproteobacteria: Desulfovibrionales0.02945Enterorhabdus caecimuris3.210460.029460.778680.45417 PAC001456_g2.154690.026090.030080.004100.03243 PAC001456_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001456_g0.03009 PAC001116_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001116_g2.776870.028990.033860.039490.15892 Desulfovibrio4.630110.0338818.032659.49910PAC001535_s group2.979090.033900.32173 EU842956_s2.175940.030540.035820.004880.03459 PAC001268_sLBacteria: Cyanobacteria: Vampirovibrio_c: FR888536_o: FR888536_f: FR888536_g2.278280.030640.035980.008570.04626 PAC001116_g2.791670.032750.038670.040760.16434 PAC001074_sPBacteria: Bacteroidetes: Bacteroidia: Bacteroidales: Muribaculaceae: PAC001074_g2.847200.038690.091550.23202 PAC002474_s2.752810.034750.041120.014050.12703Christensenellaceae/Bacteria: Firmicutes: Clostridia: Clostridiales2.510380.036920.043730.099560.16411 PAC000197_f.Bacteria: Tenericutes: Mollicutes: PAC001057_o2.675470.043750.148780.24331 PAC001090_g3.030960.043770.289150.07457 PAC001090_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001090_g0.04380 PAC001222_s2.598270.043820.234770.15567Enterorhabdus_uc2.781150.043840.070030.19067 PAC002469_sHBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: LLKB_g2.023030.039510.046990.023010.00216 PAC002553_sHBacteria: Tenericutes: Mollicutes: PAC001057_o: PAC001057_f: PAC001108_g2.468030.041260.04953 PAC001193_s2.353660.041330.049690.061000.01608Clostridiaceae3.025390.049960.344470.13263Porphyromonadaceae2.927900.049990.174990.34420ParabacteroidesGBacteria: Bacteroidetes: Bacteroidia: Bacteroi<dales: PorphyromonadaceaeFCNB_g2.644790.205950.11787 KE159605_g3.202820.050070.136600.45544 PAC001372_sMBacteria: Firmicutes: Clostridia: Clostridiales: Lachnospiraceae: PAC001372_g2.890930.050090.170400.01502 PAC002389_sUBacteria: Actinobacteria: Coriobacteriia: Coriobacteriales: Coriobacteriaceae: FCNB_g0.05012 PAC001074_g2.868140.046640.056450.108920.25634`Supplementary Table 2. 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