ࡱ> ; 7bjbjȝȝ 2hh/.:B b b b b =!!$"K:M:M:M:M:M:M:$R=@Jq:"=!=!""q:b b :888"*b b 98"K:888b kqA8p89:0:8R@8R@8R@8""8"""""q:q:8""":""""R@"""""""""X T: ISupplementary File 1. Homo sapiens hedgehog interacting protein (HHIP), mRNA NCBI Reference Sequence: NM_022475.2  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NM_022475.2" \l "goto324072750_0" Go to: LOCUS NM_022475 3555 bp mRNA linear PRI 03-JUN-2018  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NM_022475.2?from=681&to=2783" CDS 681..2783  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NM_022475.2?from=1&to=959" exon 1..959 ORIGIN 1 ggccgccggg gcccggggga cgcgctcgcg cgggggccgc cccctcccct tccctccacc 61 ctgggcgggg gcgcgcgaga agcggtgacg tcaaggggcg cgctgtggca gcacctcccc 121 gcgcgctagt taaaaagaag aagaaaagag ggaacgaaac atgagaggct gtgtgagaag 181 ctgcagccgc cggcagagga gacctcagca tcatctagag cccagcgctg gccctgcctc 241 cgcctgcccc gccgccgccg tcgccgtttc tgttcctgct actgtcccac ctaaacaact 301 cccgttacac ggacaagtga acatctgtgg ctgtcctctc cttttcttcc tcctcttcca 361 actccttctc ctcctcccac ttcccagccg cagcagaaag cccccaaccc aactgacact 421 ggcacaactg caaacggtgt catccgcaca actttatctc gctcctcggg ctcccctaag 481 gcattggacc catcgccgcg tcttttattt tttgcaaagt tgcatcgctg tacatatttt 541 tgtccccgcc acctccctct gtctctggag tgccctacag ccccgcaaac tcctcctgga 601 gctgcgccct agtgcccctg ctgggcagtg gcgttccccc ccatcctccc gcgcccagcc 661 cctgctgctc tgggcagacg atgctgaaga tgctctcctt taagctgctg ctgctggccg 721 tggctctggg cttctttgaa ggagatgcta agtttgggga aagaaacgaa gggagcggag 781 caaggaggag aaggtgcctg aatgggaacc ccccgaagcg cctgaaaagg agagacagga 841 ggatgatgtc ccagctggag ctgctgagtg ggggagagat gctgtgcggt ggcttctacc 901 ctcggctgtc ctgctgcctg cggagtgaca gcccggggct agggcgcctg gagaataaga 961 tattttctgt taccaacaac acagaatgtg ggaagttact ggaggaaatc aaatgtgcac 1021 tttgctctcc acattctcaa agcctgttcc actcacctga gagagaagtc ttggaaagag 1081 acctagtact tcctctgctc tgcaaagact attgcaaaga attcttttac acttgccgag 1141 gccatattcc aggtttcctt caaacaactg cggatgagtt ttgcttttac tatgcaagaa 1201 aagatggtgg gttgtgcttt ccagattttc caagaaaaca agtcagagga ccagcatcta 1261 actacttgga ccagatggaa gaatatgaca aagtggaaga gatcagcaga aagcacaaac 1321 acaactgctt ctgtattcag gaggttgtga gtgggctgcg gcagcccgtt ggtgccctgc 1381 atagtgggga tggctcgcaa cgtctcttca ttctggaaaa agaaggttat gtgaagatac 1441 ttacccctga aggagaaatt ttcaaggagc cttatttgga cattcacaaa cttgttcaaa 1501 gtggaataaa gggaggagat gaaagaggac tgctaagcct cgcattccat cccaattaca 1561 agaaaaatgg aaagttgtat gtgtcctata ccaccaacca agaacggtgg gctatcgggc 1621 ctcatgacca cattcttagg gttgtggaat acacagtatc cagaaaaaat ccacaccaag 1681 ttgatttgag aacagccaga gtctttcttg aagttgcaga actccacaga aagcatctgg 1741 gaggacaact gctctttggc cctgacggct ttttgtacat cattcttggt gatgggatga 1801 ttacactgga tgatatggaa gaaatggatg ggttaagtga tttcacaggc tcagtgctac 1861 ggctggatgt ggacacagac atgtgcaacg tgccttattc cataccaagg agcaacccac 1921 acttcaacag caccaaccag ccccccgaag tgtttgctca tgggctccac gatccaggca 1981 gatgtgctgt ggatagacat cccactgata taaacatcaa tttaacgata ctgtgttcag 2041 actccaatgg aaaaaacaga tcatcagcca gaattctaca gataataaag gggaaagatt 2101 atgaaagtga gccatcactt ttagaattca agccattcag taatggtcct ttggttggtg 2161 gatttgtata ccggggctgc cagtcagaaa gattgtatgg aagctacgtg tttggagatc 2221 gtaatgggaa tttcctaact ctccagcaaa gtcctgtgac aaagcagtgg caagaaaaac 2281 cactctgtct cggcactagt gggtcctgta gaggctactt ttccggtcac atcttgggat 2341 ttggagaaga tgaactaggt gaagtttaca ttttatcaag cagtaaaagt atgacccaga 2401 ctcacaatgg aaaactctac aaaattgtag atcccaaaag acctttaatg cctgaggaat 2461 gcagagccac ggtacaacct gcacagacac tgacttcaga gtgctccagg ctctgtcgaa 2521 acggctactg cacccccacg ggaaagtgct gctgcagtcc aggctgggag ggggacttct 2581 gcagaactgc aaaatgtgag ccagcatgtc gtcatggagg tgtctgtgtt agaccgaaca 2641 agtgcctctg taaaaaagga tatcttggtc ctcaatgtga acaagtggac agaaacatcc 2701 gcagagtgac cagggcaggt attcttgatc agatcattga catgacatct tacttgctgg 2761 atctaacaag ttacattgta tagtttctgg gactgtttga atattctatt ccaatgggca 2821 tttatttttt atcctgtcat taaaaaaaaa agactgttat cctgctacac actcctgtga 2881 tttcattctc ttttattaat ttaaaaataa tttccagaaa tgtgcagatc ctctgtgtgt 2941 atgtcagcat gtttgttcac atatgcacat acacatactc ataaccccta tatgcgttgt 3001 tgcataacag atgatttttt aaaatatata cttccttatg caaagtaatt tacacagaaa 3061 ttccattgta aattgataat ggatttttta tgttactaga agagattatt tgacttccca 3121 ggaattttct gtctgtaatc actaaagtca actttaatag agttttgaaa cagtactgtg 3181 caatccgatg gatctaatta aaaaaaaggc aatattttta tattaaagta ctatactagg 3241 agagaatgtt tcagaactcc ctgatgaatt tctaagtgag caacttgata taaaattgta 3301 atcttcattt ttgtcagtgt atccagttac agaatgctac acacttacct ttttattggc 3361 tgagaaatct ggttatttca tcttaatctc aagattgttt tcaagtgttt tataattaaa 3421 tcataatagc atattttaaa atcaatcttc ctaaaaggtc tgcttttatt gtatatttta 3481 tttaacaata ggcactgggt ttgtgttaca tatttatata ttttatttta tttttataat 3541 atagacatca cctag Homo sapiens HHIP antisense RNA 1 (HHIP-AS1), long non-coding RNA NCBI Reference Sequence: NR_037595.1  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NR_037595" \l "goto326320060_0" Go to: LOCUS NR_037595 1132 bp RNA linear PRI 24-MAY-2018  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NR_037595.1?from=1&to=1132" gene 1..1132  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NR_037595.1?from=1&to=313" exon 1..313  HYPERLINK "https://www.ncbi.nlm.nih.gov/nuccore/NR_037595.1?from=314&to=1132" exon 314..1132 ORIGIN >uc003ijq.2 (HHIP-AS1) length=1132 1 cgcgtccccc gggccccggc ggcctccctg ctgcggcggg gaggggcggc tagccgcgac 61 ggcggcggac ggagggggag ggccgcgagc cttcggaacc agcctcgagg gtgctgaacc 121 ccgcgcgccc gcctcgccgc ggcccccggg tgggggcgtc cacggcccgg gttcccggcg 181 ggcttggggc agggacgcag tccggagatt ccgggactgc ccggctgctg cagcccgcag 241 gctcctctct cctccccgct tcccctccgc actgcctggg ctaaaggcgg ccaagctgag 301 gctccgaaag aaaagggaaa attgcaaccc ttgcctacaa ccagactgac agcataattt 361 cttaggaatc aagaatcaat acagggttat ttctttagat taaaccttaa aagccccctt 421 ggaggctgaa gaagcagagg atagccatgc atacacttga acgtgaaaaa tggtcctctt 481 tcattggaga ggtcttcctc ttcagctaaa ccgacagagt ggtgaaaaga agaagggacc 541 ccttgttgac caaaataatc cagacaaatc aaatcggccc tttccagcaa ggagtggaac 601 agcccaaggg tggctagatc acatcttctg ctcacaccac cactgagcaa ccctctccag 661 gactgccacc tatgcatagg tcatgccctg tgcaagagca cataaagtgg gagctgaagt 721 cctgcccagg ctccattcac caagcagagc ttatgttgtt gtgtgtctgt gtctacccag 781 aggatgtggg tcctttttaa aatgtgcacc aatgcatctt gtatgagctg gcaccagctc 841 ggaccatccc accctcatac cctggtccta tccagggtta tattccctac tttagaagaa 901 ttaattattt ttatgaacgt atttagttta ttgtaaaaaa tgaaatatat gacacaaatt 961 gaaattaatt tcagaggtaa aggtcagaat attaccatgt atgtgaatta tgtttgtatg 1021 tatatgtata tatcaagaga gttatatgaa tatacatttt tgtgtatcag aagtgaggac 1081 aatttaactt tgttaagtgt ttgaaataaa attattttga gttttggaat ca 1. The proteins that bind to HHIP-AS1 was predicted by using the web ( HYPERLINK "http://rbpdb.ccbr.utoronto.ca//index.php" http://rbpdb.ccbr.utoronto.ca//index.php) ScoreRelative ScoreRBP Name10.3039431100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=2917"ZRANB28.7178165100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1262"PABPC17.3693752100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1289"FUS7.08652094100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1358"SFRS97.08652094100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1358"SFRS96.6279899100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1507"MBNL16.4668404100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1251"EIF4B6.4668404100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1251"EIF4B6.33985100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=2661"KHSRP6.33985100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=2661"KHSRP4.84132568100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1589"RBM44.84132568100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1589"RBM44.62028767100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1448"SFRS14.62028767100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1448"SFRS14.40359056100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1258"ELAVL14.40359056100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1258"ELAVL14.40359056100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1258"ELAVL14.40359056100%HYPERLINK "http://rbpdb.ccbr.utoronto.ca/proteins.php?PME_sys_operation=PME_op_View&PME_sys_rec=1258"ELAVL1 ELAVL1: ELAV like RNA binding protein 1 [ Homo sapiens (human) ] Official Full Name: ELAV like RNA binding protein 1 Ensembl: ENSG00000066044 MIM:603466 Also known as: HUR; Hua; MelG; ELAV1 Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. 2. The interaction between HHIP-AS1 and ELAVL1 was initially identified by using the web ( HYPERLINK "http://pridb.gdcb.iastate.edu/RPISeq/#" http://pridb.gdcb.iastate.edu/RPISeq/#) >sp|Q15717|ELAVL1_HUMAN MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPIT VKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNA SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM AIASLNGYRLGDKILQVSFKTNKSHK Your submission results  HYPERLINK "http://pridb.gdcb.iastate.edu/RPISeq/index.html" RNA-Protein Interaction Prediction (RPISeq) Interaction probabilitiesPrediction using RF classifier0.8Prediction using SVM classifier0.8 3. The interaction between HHIP-AS1 and ELAVL1 was further identified by using the web (http://service.tartaglialab.com/page/catrapid_group) Information about the JOB: ID: 372520 User label: ELAVL1-HHIP-AS1  HYPERLINK "http://crg-webservice.s3.amazonaws.com/submissions/2021-07/372520/output/protein.fasta" Protein sequence  HYPERLINK "http://crg-webservice.s3.amazonaws.com/submissions/2021-07/372520/output/rna.fasta" Transcript sequence Generated: 2021-07-01 03:35:01.947956 #Protein regionRNA regionInteraction PropensityDiscriminative PowerNormalized Score1251-3028-2623.41613.882251-30232-8322.98593.813251-302132-18321.89563.644251-302107-15820.09543.355251-302126-17719.57523.266176-2278-2619.56523.267176-2278-2619.56523.268176-22732-8319.16523.209176-22732-8319.16523.20 LMqrs  ҽ{g{S{g??'hJkB*CJKHOJQJ^JaJph&hJk>*B* CJKHOJQJ^Jphd*'hJkB*CJKHOJQJ^JaJph0jhJkB*CJKHOJQJU^JaJph'hJkB*CJKHOJQJ^JaJphDDD)hJk5B*CJKH$OJQJ\^Jph""")h'5B*CJKH$OJQJ\^Jph""")hP5B*CJKH$OJQJ\^Jph"""/h'h'5B*CJKH$OJQJ\^Jph"""Mr = ! m  dh-DM ,$ 2( Px 4 #\'*.25@9dh-D1$M a$$dh-D1$M a$$dh00-D1$M a$$dhx0-D1$@&M a$  f g j k   < = G  ! + l m w     P Q [ ӭӭ'hJk0JB*CJOJQJ^JaJph*hJk0J5B*CJOJQJ^JaJph#hJkB*CJOJQJ^JaJph'hJk0JB* CJOJQJ^JaJphd*'hJk0JB*CJOJQJ^JaJph0jhJk0JB*CJOJQJU^JaJph3 Q 5 eI-y]A%q U dh-DM   4 5 ? #deoHIS,-7xy\]g@AK$%/pq{ TU_#hJkB*CJOJQJ^JaJph'hJk0JB*CJOJQJ^JaJphVU9iM1}aE)udh dh-DM 89C'his LMW01;|}`akDEO()3tu hJko(#hJkB*CJOJQJ^JaJph'hJk0JB*CJOJQJ^JaJphPKLRSTֽkR>R'hJk0JB*CJOJQJ^JaJph0jhJk0JB*CJOJQJU^JaJph*hJkB*CJKHOJQJ^JaJo(ph'hJkB*CJKHOJQJ^JaJph&hJk>*B* CJKHOJQJ^Jphd*'hJkB*CJKHOJQJ^JaJph0jhJkB*CJKHOJQJU^JaJph'hJkB*CJKHOJQJ^JaJphDDD)hJk5B*CJKH$OJQJ\^Jph"""ThO3 dh dh-DM ,$ 2( Px 4 #\'*.25@9dh-D1$M a$$dh-D1$M a$$dh00-D1$M a$$dhx0-D1$@&M a$OPTUghi 'NOYҾҾҾҾҾpp`RR`RR`hJkCJOJQJ^JaJhJk0JCJOJQJ^JaJ*hJk0J5B*CJOJQJ^JaJph#hJkB* CJOJQJ^JaJph&hJkB*CJOJQJ^JaJo(ph#hJkB*CJOJQJ^JaJph'hJk0JB*CJOJQJ^JaJph0jhJk0JB*CJOJQJU^JaJph'hJk0JB* CJOJQJ^JaJphd* 23=~  ! b c m !!F!G!Q!!!!!!!"*"+"5"v"w"""""####Z#[#e######ѼhJk5CJKHaJo(*hJkB*CJKHOJQJ^JaJo(ph(hJk5B*KH$OJQJ\^Jo(ph"""!hJk0JCJOJQJ^JaJo(hJk0JCJOJQJ^JaJhJkCJOJQJ^JaJ8 c G!!!+"w""#[####J$K$Q$`$i$ $dh$1$Ifa$dh1$,$ 2( Px 4 #\'*.25@9dh-D1$M a$ dh-DM ######$$$G$H$I$J$K$P$Q$_$`$h$i$j$t$u$y$z${$$$$$$$$$ԾԄqqqqqqqaaaaYUYaYaaaahJkjhJkUhJkCJKHOJQJ^JaJ$hJk5CJKHOJQJ\^JaJ*hJkB*CJKHOJQJ^JaJo(ph%hJk0J5CJKHOJQJ^JaJ!hJk5CJKHOJQJ^JaJ*jhJk5CJKHOJQJU^JaJ$hJk5CJKHOJQJ^JaJo(hJk5CJKHaJo(hJk5CJKHaJ!i$j$u$z$$L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4ap$$$$h%L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4ap$$$$%_%`%f%g%h%i%r%s%w%x%y%%%%%%%%%%%%&[&\&a&b&c&d&n&o&s&t&u&&&&&&&&&&&&'X'Y'^'_'`'a'j'k'o'p'q''''''''''''(T(U(Z([(\(](d(e(i(j(k(hJkCJKHOJQJ^JhJkjhJkUhJkCJKHOJQJ^JaJTh%i%s%x%%L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4ap%%%%c&L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4apc&d&o&t&&L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4ap&&&&`'L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4ap`'a'k'p''L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4ap''''\(L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4ap\(](e(j((L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4apk(((((((((((()L)M)R)S)T)U)_)`)d)e)f))))))))))))*I*J*N*O*P*Q*[*\*`*a*b************+F+G+L+M+N+O+Y+Z+^+_+`+++'hJkB*CJKHOJQJ^JaJphhJkCJKHOJQJ^JaJhJkCJKHOJQJ^JjhJkUhJkG((((T)L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4apT)U)`)e))L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4ap))))P*L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4apP*Q*\*a**L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4ap****N+L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4apN+O+Z+_++L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4ap++++++++++,E,F,L,M,N,O,Y,Z,^,_,`,,,,,,,,,,,,-E-F-L-M-N-O-P-Q-W-X-------------..../0000 hJkCJo( hJkCJhJk5CJo( hJk5CJhJk5B*CJo(phhJk'hJkB*CJKHOJQJ^JaJphjhJkU#hJkB*CJKHOJQJ^Jph@++++N,L>>> $dh$1$Ifa$kd$$IfF v f 06    22 <4apN,O,Z,_,,L>>> $dh$1$Ifa$kd $$IfF v f 06    22 <4ap,,,,N-L>>> $dh$1$Ifa$kd"$$IfF v f 06    22 <4apN-O-P-Q----.0LGGGGGGGdhkd$$$IfF v f 06    22 <4ap00000000000a11102m222222K3e3 $dh$1$Ifa$ dh[$\$dh$dha$dh000000000000000000001117181^1_1`1a1p1q111112/202l2m222222ƸzqhJkCJaJo(hJkB*o(phhJkB*phhJk0J5CJaJ#jhJk5B*CJUaJphhJk5B*CJaJo(phhJk5B*CJaJphhJk5CJKHaJo(hJk5CJKHaJhJk5CJaJhJk5CJaJo(hJk5B*CJo(ph,22222333I3J3K3d3e3f3g3h3i3j333333333333333ͻͧͻuuuuc#hJkB*CJOJQJ^JaJphhJkCJKHOJQJ^JhJkCJKHOJQJ^JaJ'hJk5>*CJKHOJQJ\^JaJ'hJk0JB*CJ$OJQJ^JaJ$ph33#hJkB*CJ$OJQJ^JaJ$phf,jhJkB*CJ$OJQJU^JaJ$phf#hJkB*CJOJQJ^JaJphfffhJkCJaJo(e3f3g3h3i3IQkd$$If   634` ap $dh$1$Ifa$Vkd&$$If   6234` ap i3j3333 $dh$1$Ifa$QkdA$$If   634` ap 33333m___ $dh$1$Ifa$kd$$IfF   6    234` ap3333333333333mhhhhhhhhhhhdhkd$$IfF   6    234` ap 33333333333333333333444L4M4N4h4i4s4t444k]]]]hJkB*OJQJ^Jphfff)hJk5B* CJOJQJ\^JaJph!hJk5B* OJQJ\^Jph#hJkB*CJOJQJ^JaJphhJk5B*CJaJo(phhJk5B*CJaJphhJk5CJKHaJo(hJk5CJKHaJhJk5CJaJhJk5CJaJo(&hJkB*CJOJQJ^JaJo(ph3N4i455555555 dh$If$dha$$dh[$\$a$dh<dh 4444555 55i5j5}5~55555555555555555666 6 6 6 666666666666 6'6(6-6.636466676;6<6=6>6?6F6G6N6O6߽ hJkaJo(hJkOJQJ^JaJ hJkaJ#hJkB*CJOJQJ^JaJphhJk0JB* OJQJ^JphhJkB*OJQJ^Jphfff$jhJkB*OJQJU^Jphfff@566 6668//// dh$Ifkdb$$IfT4ֈJ e0634aT6666 6(6.64676<6=6?6G6O6U6X6]6^6`6h6p6v6y6~6666FfU#FfFf)Ff dh$IfO6T6U6W6X6\6]6^6_6`6g6h6o6p6u6v6x6y6}6~66666666666666666666666666666666666666666666666666666666666677 7 777777777 hJkaJo(hJkOJQJ^JaJ hJkaJZ666666666666666666666666666Ff1Ff.Ff*Ff& dh$If667 777777dhFfC5 dh$If77hJkCJaJo(0182P. 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