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A,I,     }|  b            A~I~  i      20% - Accent2A" 20% - Accent2 % 20% - ?? 1w 20% - ?? 3w 20% - ?? 4w 20% - ?? 5w 20% - ?? 6w 40% - Accent1M 40% - Accent1 L % 40% - ?? 2%  40% - ?? 3%  40% - ?? 4%  40% - ?? 5%  40% - ?? 6%  60% - Accent3M( 60% - Accent3 23GY % 60% - ?? 1%  60% - ?? 2%  60% - ?? 4w 60% - ?? 5% ! 60% - ?? 6% "Bad-Bad %# Calculationi Calculation% $ Comma%( Comma [0]&&Currency'. Currency [0](Good/Good a% ) Heading 1( Heading 1 * Heading 2; Heading 2%?d + Heading 4( Heading 4,InputiInput ??v%  -NeutralANeutral  W%3Normal %.Noteb Note  /$Percent0Title Title1Total1Total % 2?? 3?? 3?????? 4?? 1?? 5?? 2?? 6?? 3?? 7?? 4?? 8?? 5?? 9?? 6?? :?????? ;??????<???? =??????83ffff̙3f3fff3f3f33333f33333UTable S4  T fI0Mh>n  dMbP?_*+%,[&ffffff?'ffffff?(?)?"[D S4333333?333333?U f  ,? ? , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,d@\Supplementary Table 4. The results of GO analysis (Biological Process) in GSE33382 data set.?geneSet? description ?size?overlap?expect?enrichmentRatio?pValue ?FDR?userId GO:0010273$detoxification of copper ion,@@ý?X3K@>>>k>%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:1990169%stress response to copper ion,@@ý?X3K@>>>k>%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0061687,$detoxification of inorganic compound.@@?}I@>F>>>%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0097501$stress response to metal ion0@@Cb4M?8eM9H@>(/>>En>%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0071294%cellular response to zinc ion6@@qN?x A@>6mٳK>>8xpc>%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0071280'cellular response to copper ion:@@x?A_=@>}d>>M?%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0006882%cellular zinc ion homeostasisA@@!0gV?V%6@>B$gP>>%6?%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E  GO:0071276(  cellular response to cadmium ion B@@ ĝk? $D5@ >+NSf> >Ǻ6?% MT1F;MT1X;MT1A;MT1M;MT2A;MT1E  GO:0055069 zinc ion homeostasis B@@ W_~> >i;.8?% MT1F;MT1X;MT1A;MT1M;MT2A;MT1E  GO:0046688 response to copper ion E@@ MR? D@t2@ >ݛȔ[Ϫ> > !G?% MT1F;MT1X;MT1A;MT1M;MT2A;MT1E  GO:0010043 response to zinc ion K@@ Z l!? ,@ >7P> *Oh?% MT1F;MT1X;MT1A;MT1M;MT2A;MT1E  GO:00712410 (cellular response to inorganic substance  j@$@ `M3? ]Y@ >f*1>  .p?= 5MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;MTR;SLC25A23;CFLAR;DLG4 GO:0046686response to cadmium ionO@@s|T|5?V(@> >`uy?%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0098754detoxification]@@c{7:?w@>Ml^0?<yN?)!MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;TPO GO:0071248&cellular response to metal ion g@ @wL?OX@>g>?53ޭ?3+MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;SLC25A23;DLG4 GO:00469161)cellular transition metal ion homeostasisZ@@чѸ??^a@>v'?N{?%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0031103axon regenerationE@@_$M?=?: (@>N ^5?84?MAP2K1;MTR;LAMB2;EPHA4 GO:0051099&positive regulation of bindingf@@5J?'@>3ۃ@?u_K?/'GTF2B;PLXND1;DERL1;NVL;HES1;PYGO2;EPHA4 GO:0055076( transition metal ion homeostasis`@@)e`?`Hϡ#@>u D? ;'?%MT1F;MT1X;MT1A;MT1M;MT2A;MT1E GO:0031102&neuron projection regenerationJ@@x?9?#@>NwxF?EՍ=?MAP2K1;MTR;LAMB2;EPHA4 GO:0036018+#cellular response to erythropoietin@@3ý?D@tB@>S?$/-? MT1X;MT2A GO:0048645animal organ formationN@@Ұx7?\]A߅ @g4T?$/-?MAP2K1;GNG5;SPRY1;HES1 GO:0036017"response to erythropoietin @@Cb4M?:ɘ3&@@TI*tZ?Nl? MT1X;MT2A GO:0048678response to axon injuryP@@)e`?x-@cH]?a?MAP2K1;MTR;LAMB2;EPHA4 GO:0010038response to metal ion@v@"@/] @Bꍒ ! @ ذ]?a?91MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;SLC25A23;CCND1;DLG4 GO:0003263!cardioblast proliferation"@@dkձ?:<@`N~`?_? GNG5;HES1 GO:0048708!astrocyte differentiationQ@@ugV?Mή@L& Xa?_?MAP2K1;HES1;LAMB2;EPHA4 GO:0051098regulation of bindingv@"@@(X]X @7WIB>b?,#?91SLN;GTF2B;DISC1;PLXND1;DERL1;NVL;HES1;PYGO2;EPHA4 GO:0003266E=regulation of secondary heart field cardioblast proliferation$@@uг?}9@{$ e?U0? GNG5;HES1 GO:0003156,$regulation of animal organ formationB@@W ,? ,  GO:0010035' response to inorganic substance @&@ )e`@ Z<5@ Ghh? "b?C ;MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;MTR;SLC25A23;CCND1;CFLAR;DLG4! GO:0031099! regeneration!g@@!A6?!@!*a;R\i?!"b?*!"MAP2K1;MTR;CCND1;CFLAR;LAMB2;EPHA4" GO:0003264/"'regulation of cardioblast proliferation"&@@"s=P˵?" |Rb}7@"Aɖi?""b?" GNG5;HES1# GO:0045926%#negative regulation of growth#@o@@#[?#:} @#ѬNk?#aq?,#$MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;CDKN2A$ GO:0050772+$#positive regulation of axonogenesis$@T@@$??$3Y*@$ |m?$KU3s?!$PLXNA2;MAP2K1;MAP6;PLXND1% GO:1902287E%=semaphorin-plexin signaling pathway involved in axon guidance%(@@%6A&:Ƿ?%$D5@%7n?%KU3s?% PLXNA2;PLXND1& GO:00725036&.cellular divalent inorganic cation homeostasis&}@$@&XJ @&>z|@&|z*n?&KU3s??&7MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;SLC25A23;CCL28;HTR2A;DLG4' GO:1902285R'Jsemaphorin-plexin signaling pathway involved in neuron projection guidance'*@@'x¹?'3\?3@'ßNjIq?~ '?' PLXNA2;PLXND1( GO:00313992(*regulation of protein modification process(@8@((bj+@(h=?(r؍Hr?~ (?(MAP2K1;SOCS4;RWDD3;TRIB2;RAB3GAP2;EPHB4;ABCA7;SPTBN4;SPRY1;CDKN2A;HEXIM2;CCND1;DERL1;RCHY1;BCL10;HTR2A;CARD9;POMT1;CFLAR;HES1;DLG4;PYGO2;IFNA17;EPHA4) GO:0010976<)4positive regulation of neuron projection development)p@@)c_X@)o`g @)DwTbr?~ )?2)*PLXNA2;MAP2K1;MAP6;PLXND1;CFLAR;DLG4;EPHA4* GO:0072507-*%divalent inorganic cation homeostasis*~@$@*F@*흔 @*q ut?~ *??*7MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;SLC25A23;CCL28;HTR2A;DLG4+ GO:0009111!+vitamin catabolic process+,@@+ý?+D@t2@+w+,t?~ +?+ CYP4F2;MTHFS, GO:0010770M,Epositive regulation of cell morphogenesis involved in differentiation,`b@@,;n4?,ϓ@,{fqw?~ ,?',PLXNA2;MAP2K1;MAP6;PLXND1;EPHA4- GO:0043624,-$cellular protein complex disassembly-@j@@-0Z?-<ή @-y=x?~ -?--%MRPS18C;MRPL35;SLN;VILL;SPTBN4;MRPL40. GO:0032092..&positive regulation of protein binding.@W@@.pV ?.Nzw:@.i8x?~ .?.PLXND1;DERL1;NVL;EPHA4/ GO:0009620/response to fungus/H@@/hT':?/͘3& @/fx?~ /?/DCD;BCL10;CARD90 GO:0009109"0coenzyme catabolic process00@@0Cb4M?0ޘ3&0@0*fO7{?~ 0?0 CYP4F2;MTHFS1 GO:0071732)1!cellular response to nitric oxide10@@1Cb4M?1ޘ3&0@1*fO7{?~ 1?1 MTR;CFLAR2 GO:0006590"2thyroid hormone generation20@@2Cb4M?2ޘ3&0@2*fO7{?~ 2?2 SLC5A5;TPO3 GO:0071786:32endoplasmic reticulum tubular network organization30@@3Cb4M?3ޘ3&0@3*fO7{?~ 3?3RAB3GAP2;REEP14 GO:0048489"4synaptic vesicle transport4 c@@4mW?4AY@4f;oϮ{?~ 4?&4SNAP29;SYN1;PPFIA2;HTR2A;AP3B15 GO:009748065.establishment of synaptic vesicle localization5 c@@5mW?5AY@5f;oϮ{?~ 5?&5SNAP29;SYN1;PPFIA2;HTR2A;AP3B16 GO:00516406organelle localization6p@(@6D+I=@6,`@6,_o|?~ 6?Q6ISNAP29;PLXNA2;GPSM2;SYN1;MAP6;SPRY1;RIOK2;TMEM67;PPFIA2;HTR2A;CNIH3;AP3B17 GO:00359047aorta development7I@@79ɭC?7JIf@7.z}?~ 7?7ADAMTS9;PLXND1;HES18 GO:0031346;83positive regulation of cell projection organization8v@ @8+/G @8\p5@8F~?~ 8?78/PLXNA2;MAP2K1;MAP6;PALM;PLXND1;CFLAR;DLG4;EPHA49 GO:0050769+9#positive regulation of neurogenesis9{@"@9ʌO @9K@9"|`?~ 9?=95PLXNA2;MAP2K1;MAP6;DISC1;PLXND1;CFLAR;HES1;DLG4;EPHA4: GO:0033599A:9regulation of mammary gland epithelial cell proliferation:2@@:ĝk?:,@:qF&R-?~ :?: CCND1;PYGO2; GO:2000136H;@regulation of cell proliferation involved in heart morphogenesis;2@@;ĝk?;,@;qF&R-?~ ;?; GNG5;HES1< GO:0097479%<synaptic vesicle localization<d@@<|O?<Rz{@<BH̢f?~ <?&<SNAP29;SYN1;PPFIA2;HTR2A;AP3B1= GO:0007269"=neurotransmitter secretion=d@@=&5o?=JInQ@=z#n܂?~ =?&=SNAP29;SYN1;NRXN2;PPFIA2;HTR2A> GO:0099643#>signal release from synapse>d@@>&5o?>JInQ@>z#n܂?~ >?&>SNAP29;SYN1;NRXN2;PPFIA2;HTR2A? GO:0071731 ?response to nitric oxide?3@@? ??532+@?^"j?~ ??? MTR;CFLARDNlG@ ,A ,B ,C ,D ,E ,F ,G ,H ,I ,J ,K ,L ,M ,N ,O ,P ,Q ,R ,S ,T ,U ,V ,W ,X ,Y ,Z ,[ ,\ ,] ,^ ,_ ,@ GO:19021706@.cellular response to reactive nitrogen species@3@@@ ?@532+@@^"j?~ @?@ MTR;CFLARA GO:0061323:A2cell proliferation involved in heart morphogenesisA3@@A ?A532+@A^"j?~ A?A GNG5;HES1B GO:0042226*B"interleukin-6 biosynthetic processB3@@B ?B532+@B^"j?~ B?B BCL10;CARD9C GO:00703744C,positive regulation of ERK1 and ERK2 cascadeC`m@@C.?Cvc @CY`^g?~ C?,C$MAP2K1;EPHB4;ABCA7;HTR2A;CFLAR;EPHA4D GO:0070372+D#regulation of ERK1 and ERK2 cascadeD@s@@D@Ev@DMRb}@DF`"_?~ D?2D*MAP2K1;EPHB4;ABCA7;SPRY1;HTR2A;CFLAR;EPHA4E GO:0050808Esynapse organizationEx@ @EN@EH~y@ENE?~ E?6E.SYN1;NRXN2;PALM;PLXND1;PPFIA2;LAMB2;DLG4;EPHA4F GO:0042403)F!thyroid hormone metabolic processF4@@Fu?FR)@Fe ?~ F?F SLC5A5;TPOG GO:0031401;G3positive regulation of protein modification processG@1@G#l"@G<ή?G%T M[!?~ G?pGhMAP2K1;RWDD3;RAB3GAP2;EPHB4;ABCA7;CCND1;DERL1;RCHY1;BCL10;HTR2A;CARD9;POMT1;CFLAR;HES1;DLG4;IFNA17;EPHA4H GO:0055065Hmetal ion homeostasisH@&@H]O@HFa@HZ}?~ H?FH>MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;SLC25A23;CCL28;CYP4F2;HTR2A;DLG4I GO:00509512I*sensory perception of temperature stimulusI5@@IMR?IV(@I u8?~ I?I KCNK4;HTR2AJ GO:1902003,J$regulation of amyloid-beta formationJ5@@JMR?JV(@J u8?~ J?J ABCA7;EPHA4K GO:0006622%Kprotein targeting to lysosomeK5@@KMR?KV(@K u8?~ K?K AP4M1;AP3B1L GO:0006875&Lcellular metal ion homeostasisLx@$@L %?TN@LnfA}@LcT?~ L??L7MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;SLC25A23;CCL28;HTR2A;DLG4M GO:0032835Mglomerulus developmentMN@@MҰx7?M Hj@MlS`!?~ M?MCFLAR;HES1;LAMB2N GO:0048679'Nregulation of axon regenerationN6@@NqN?N |Rb}'@N}j?~ N?N MAP2K1;EPHA4O GO:0043062,O$extracellular structure organizationOy@ @ON @O3)ǫ@O {މ?~ O?9O1FMOD;EFEMP2;ABCA7;ADAMTS9;POMT1;CFLAR;SMOC2;LAMB2P GO:0051187"Pcofactor catabolic processPO@@Ps|T|5?PV@P,xZI?~ P?PTPO;CYP4F2;MTHFSQ GO:0032984.Q&protein-containing complex disassemblyQ0t@@Q!g>@QOf@Q+B8gg?~ Q?4Q,SNAP29;MRPS18C;MRPL35;SLN;VILL;SPTBN4;MRPL40R GO:0050770"Rregulation of axonogenesisRf@@R5J?R@ @R[?~ R?'RPLXNA2;MAP2K1;MAP6;PLXND1;EPHA4S GO:0070371SERK1 and ERK2 cascadeS`t@@S8!_/@S%R[1@S?~ S?2S*MAP2K1;EPHB4;ABCA7;SPRY1;HTR2A;CFLAR;EPHA4T GO:00722432T*metanephric nephron epithelium developmentT7@@T~??T-69w&@T!{|?~ T?T HES1;LAMB2U GO:0072012*U"glomerulus vasculature developmentU7@@U~??U-69w&@U!{|?~ U?U CFLAR;HES1V GO:00001324V,establishment of mitotic spindle orientationV7@@V~??V-69w&@V!{|?~ V?V GPSM2;SPRY1W GO:0051656/W'establishment of organelle localizationW~@"@WF@WHer@Ww^ ?~ W?>W6SNAP29;GPSM2;SYN1;SPRY1;RIOK2;PPFIA2;HTR2A;CNIH3;AP3B1X GO:2000209Xregulation of anoikisX8@@XIg(:?X$D%@XqE?~ X?X ANKRD13C;MCL1Y GO:0051642Ycentrosome localizationY8@@YIg(:?Y$D%@YqE?~ Y?Y PLXNA2;GPSM2Z GO:0016079#Zsynaptic vesicle exocytosisZ^@@Z1!7?Z\]A߅@Z\?~ Z? ZSNAP29;SYN1;PPFIA2;HTR2A[ GO:0007610[behavior[0@$@[ @[uu3@[78%7Ž?~ [?D[<NRXN2;NAGLU;DMRTA1;ABCA7;KCNK4;SPTBN4;MORC1;HTR2A;DLG4;EPHA4\ GO:0009636#\response to toxic substance\0@"@\a9@\)bA$@\ ?~ \?4\,MT1F;MT1X;MT1A;MT1M;MT2A;MT1E;TPO;INMT;CCND1] GO:0061437,]$renal system vasculature development]9@@]Si?] *ǫ$@]%  Oh+'0x8@L X dp???QC@G=׮@: ՜.+,00 8@ H ]  Table S4  Worksheets  !"#$%&'()*+,-./012345679:;<=>?ABCDEFGRoot EntryF k]Book nSummaryInformation(8DocumentSummaryInformation8@