Research Paper Volume 1, Issue 4 pp 412—424

Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions

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Figure 4. Tissue distribution of Sirt1 and TXNIP in mice and their regulation by resveratrol and DHEA. Mice CD1 strain were injected (i.p.) with 10 mg/Kg of either resveratrol or DHEA and after 2 days, the animals were sacrificed and organs harvested and processed by Western blot for the expression of Sirt1 and TXNIP. Staining with GAPDH was used as a loading control.