Priority Research Paper Volume 1, Issue 6 pp 515—528

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy


Figure 5. Resveratrol inhibits S6K1 in intact cells. (A) NIH/3T3 or HEK293 cells were treated for 30 minutes with increasing doses of resveratrol and whole cell extracts were western blotted for the indicated proteins. (B) WT or two separate lines of SIRT1-/- MEFs (A and B) were treated with increasing doses of resveratrol for 30 minutes and analyzed by western blot.