Research Perspective Volume 1, Issue 7 pp 664—668

"Shping 2" different cellular localizations - a potential new player in aging processes


Figure 1. Shp-2 reduces endogenous ROS formation. Endothelial cells were transfected with empty vector (EV), Shp-2 wt or Shp-2(C459S) and endogenous ROS formation was measured using FACS analysis. *p<0.05 versus Shp-2 wt. **p<0.05 versus EV. Data are means +/- SEM (n=6). The Western blot on the right demonstrates expression of Shp-2 wt and Shp-2(C459S), which were detected with anti-myc antibody.