Research Paper Volume 1, Issue 7 pp 622—636
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
Figure 8A. The two mutations, fob1Δ and afo1Δ were combined in a haploid strain from a meiotic tetrad obtained from an isogenic cross. Wild type, the two single mutants and the double mutant were tested for mother cell-specific lifespan. The fob1 mutation does not further increase the lifespan of the afo1 mutant strain (p<0.02).