Research Paper Volume 1, Issue 9 pp 803—817
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase
Figure 8. TTP protein expression is lost in human cervical cancer. (A) Immunohistochemical detection of TTP expression in normal cervix and squamous cell carcinoma. Representative tissue sections were examined for TTP expression and counterstained with hematoxylin. Original magnification x 200. (B) Immunoreactivity scores (IRS) for TTP expression in tissue sections of normal cervix and squamous cell carcinoma. The line indicates the division of samples with high IRS from 7-12 and low IRS from 0-6.